Some Characteristics And Allopurinol Release Of Carrageenan/ Allopurinol Films Using Polyethylene Oxide As A Dispersion Aid Agent

Chinh Thuy Nguyen, Phuong Thi Nguyen, Manh Quoc Vu, Hoang Thai, Trung Quoc Vu

Abstract


This paper presents the effect of carrageenan (CG) on some characteristics and drug release of allopurinol in the presence of polyethylene oxide (PEO) as a dispersion aid agent. The samples were prepared in film shape by solution method, in which, the content of PEO was changed from 1 wt.% to 5 wt.% and the content of allopurinol was fixed at 10 wt.% in comparison with carrageenan weight. FTIR , FESEM, UV-Vis methods were used to evaluate characterizations and morphology of CG/PEO/allopurinol films.


Keywords


Carrageenan, drug release, drug loading capacity, allopurinol, morphology.

References


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DOI: https://doi.org/10.15625/2525-2518/58/2/13870 Display counter: Abstract : 27 views.

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