Some characteristics and allopurinol release of carrageenan/ allopurinol films using polyethylene oxide as a dispersion aid agent

Nguyen Thi Phuong; Nguyen Thuy Chinh; Vu Quoc Manh; Thai Hoang; Vu Quoc Trung

doi:10.15625/2525-2518/58/2/13870

Author affiliations

Authors

Nguyen Thi Phuong Dai Nam University, 56 Vu Trong Phung, Thanh Xuan, Ha Noi, Viet Nam
Nguyen Thuy Chinh Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Vu Quoc Manh Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Thai Hoang Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Vu Quoc Trung Faculty of Chemistry, Hanoi National University of Education, 136 Xuan Thuy Road, Cau Giay, Ha Noi, Viet Nam

DOI:

https://doi.org/10.15625/2525-2518/58/2/13870

Keywords:

Carrageenan, drug release, drug loading capacity, allopurinol, morphology.

Abstract

This paper presents the effect of carrageenan (CG) on some characteristics and drug release of allopurinol in the presence of polyethylene oxide (PEO) as a dispersion aid agent. The samples were prepared in film shape by solution method, in which, the content of PEO was changed from 1 wt.% to 5 wt.% and the content of allopurinol was fixed at 10 wt.% in comparison with carrageenan weight. FTIR , FESEM, UV-Vis methods were used to evaluate characterizations and morphology of CG/PEO/allopurinol films.

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