Influence of polyethylene oxide content on some characteristics of PLA/CS films loading nifedipine

Nguyen Thuy Chinh, Trang Thi Thu Nguyen, Tran Thi Mai, Do Van Cong, Mai Duc Huynh, Tran Huu Trung, Vu Viet Thang, Thai Hoang, Nguyen Vu Giang
Author affiliations

Authors

  • Nguyen Thuy Chinh Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Trang Thi Thu Nguyen Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Tran Thi Mai Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Do Van Cong Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Mai Duc Huynh Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Tran Huu Trung Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Vu Viet Thang Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Thai Hoang Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
  • Nguyen Vu Giang Institute for Tropical Technology, Vietnam Academy of Science and Technology, No 18, Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam

DOI:

https://doi.org/10.15625/2525-2518/55/6/9617

Keywords:

Polyethylene oxide, compatibility, nifedipine, PLA/CS, morphology, hydrolysis

Abstract

This work mentions the effect of polyethylene oxide (PEO) content on some characteristics and properties of polylactic acid (PLA)/chitosan (CS) films loading nifedipine (NIF). The water contact angle, droplet size values and Field Emission Scanning Electron Microscopy (FESEM) images  of the films are used to investigate their morphology and hydrophobicity. The obtained results show that the hydrophobic property of the PLA/CS/NIF films is improved by the presence of PEO. Besides, the PLA/CS/NIF films containing PEO have tighter structure and water absorbed ability less than those of the PLA/CS/NIF films

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Published

11-12-2017

How to Cite

[1]
N. T. Chinh, “Influence of polyethylene oxide content on some characteristics of PLA/CS films loading nifedipine”, Vietnam J. Sci. Technol., vol. 55, no. 6, pp. 716–724, Dec. 2017.

Issue

Vol. 55 No. 6 (2017)

Section

Materials

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