Secondary metabolites produced by marine actinomycete Streptomyces sp. G246

Do Thi Quynh; Doan Thi Mai Huong; Tran Van Hieu; Truong Bich Ngan; Le Thi Hong Minh; Vu Thi Quyen; Nguyen Thi Hoang Anh; Brian T. Murphy; Phan Van  Cuong

doi:10.15625/2525-2518/58/6/15176

Author affiliations

Authors

Do Thi Quynh Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam
Doan Thi Mai Huong Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam
Tran Van Hieu Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam
Truong Bich Ngan Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam
Le Thi Hong Minh Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam
Vu Thi Quyen Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam
Nguyen Thi Hoang Anh Thaibinh Medical College, 290 Phan Ba Vanh, QuangTrung, Thai Binh, Viet Nam
Brian T. Murphy Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60607, USA
Phan Van Cuong Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Street, Cau Giay, Ha Noi, Viet Nam``

DOI:

https://doi.org/10.15625/2525-2518/58/6/15176

Keywords:

Streptomyces, marine microorganism, actinomycete, antimicrobial, solid state fermentation

Abstract

In a recent study, we described two new lavandulylated flavonoids, along with eight known compounds from the culture broth of a Streptomyces sp. (strain G246), isolated from the sponge Halichondria panicea, collected in the sea of Son Tra peninsula (Da Nang). A comparison study was conducted to differentiate between solid and liquid fermentation technique for secondary metabolites production of strain G246. In this paper, we report the isolation and structural characterization of 9 secondary metabolites (1-9) from strain G246 by solid state fermentation. Compound 3 was the only one similarity between these fermentation techniques.

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