PREPARATION OF ERLOTINIB HYDROCHLORIDE

Ta Van Dai, Le Tat Thanh, Pham Quoc Long, Tran Thi Thu Thuy
Author affiliations

Authors

  • Ta Van Dai Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology
  • Le Tat Thanh
  • Pham Quoc Long
  • Tran Thi Thu Thuy

DOI:

https://doi.org/10.15625/0866-708X/53/6/5239

Keywords:

Erlotinib, non small cell lung cancer, synthesis.

Abstract

Erlotinib hydrochloride (Tarceva) is a targeted cancer therapy drug approved for treatment of non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer. An efficient and economical synthetic method of title compound from ethyl 3,4-dihydroxybenzoate is described in 6 steps with overall yield of 51 %.

Downloads

Download data is not yet available.

Downloads

Published

23-12-2015

How to Cite

[1]
T. V. Dai, L. T. Thanh, P. Q. Long, and T. T. T. Thuy, “PREPARATION OF ERLOTINIB HYDROCHLORIDE”, Vietnam J. Sci. Technol., vol. 53, no. 6, p. 789, Dec. 2015.

Issue

Section

Articles

Most read articles by the same author(s)

<< < 1 2