Polyhydroxypregnane glycosides from Dregea volubilis

Phan Tuan Phuong; Phan Thi Lan Anh; Nguyen Xuan Nhiem; Nguyen Thi Kim Thuy; Phan Van Kiem

doi:10.15625/2525-2518/58/4/14818

Polyhydroxypregnane glycosides from Dregea volubilis

Phan Tuan Phuong, Phan Thi Lan Anh, Nguyen Xuan Nhiem, Nguyen Thi Kim Thuy, Phan Van Kiem

Author affiliations

Authors

Phan Tuan Phuong
Phan Thi Lan Anh Center for High Technology Development, VAST, 18 Hoang Quoc Viet, Ha Noi, Viet Nam
Nguyen Xuan Nhiem Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Nguyen Thi Kim Thuy Center for High Technology Development, VAST, 18 Hoang Quoc Viet, Ha Noi, Viet Nam
Phan Van Kiem

DOI:

https://doi.org/10.15625/2525-2518/58/4/14818

Keywords:

Dregea volubilis, Apocynaceae, polyhydroxypregnane glycoside.

Abstract

Four known polyhydroxypregnane glycosides, dregeoside Da1 (1), volubiloside A (2), drevoluoside N (3), and volubiloside C (4) were isolated from the methanol extract of the leaves of Dregea volubilis. Their structures were elucidated by 1D-, 2D-NMR, spectra and comparing with those reported in the literature.

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References

V. V. Chi. Dictionary of Medicinal Plants in Vietnam. Medical Publishing House, Hanoi, 253-254 (2012).

S. Yoshimura, H. Narita, K. Hayashi, H. Mitsuhashi. Studies on the constituents of Asclepiadaceae plants. LIX. The structures of five new glycosides from Dregea volubilis (L.) Benth. Chemical and Pharmaceutical Bulletin, 33, 2287-2293 (1985).

N. P. Sahu, N. Panda, N. B. Mandal, S. Banerjee, K. Koike, T. Nikaido. Polyhydroxypregnane glycosides from the flowers of Dregea volubilis. Phytochemistry, 61, 383-388 (2002).

Y. Zhang, M. Xu, D. Wang, H. Zhu, C. Yang. Application of c-3,11,12,20-tetra-substituted c-21 steroid derivatives and their pharmaceutical composition in preparation of drugs for treating epilepsy.China Patent CN102924554A; (2013), 1-27.

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Published

13-07-2020

How to Cite

[1]

P. Tuan Phuong, P. T. L. Anh, N. X. Nhiem, N. T. K. Thuy, and P. Van Kiem, “Polyhydroxypregnane glycosides from Dregea volubilis”, Vietnam J. Sci. Technol., vol. 58, no. 4, pp. 426–433, Jul. 2020.

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Issue

Vol. 58 No. 4 (2020)

Section

Natural Products

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