POLYHYDROXYPREGNANE GLYCOSIDES FROM DREGEA VOLUBILIS

Authors

  • Phan Van Kiem
  • Phan Tuan Phuong

DOI:

https://doi.org/10.15625/2525-2518/58/4/14818

Keywords:

Dregea volubilis, Apocynaceae, polyhydroxypregnane glycoside.

Abstract

Four known polyhydroxypregnane glycosides, dregeoside Da1 (1), volubiloside A (2), drevoluoside N (3), and volubiloside C (4) were isolated from the methanol extract of the leaves of Dregea volubilis. Their structures were elucidated by 1D-, 2D-NMR, spectra and comparing with those reported in the literature.

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Author Biography

Phan Van Kiem

Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam

References

V. V. Chi. Dictionary of Medicinal Plants in Vietnam. Medical Publishing House, Hanoi, 253-254 (2012).

S. Yoshimura, H. Narita, K. Hayashi, H. Mitsuhashi. Studies on the constituents of Asclepiadaceae plants. LIX. The structures of five new glycosides from Dregea volubilis (L.) Benth. Chemical and Pharmaceutical Bulletin, 33, 2287-2293 (1985).

N. P. Sahu, N. Panda, N. B. Mandal, S. Banerjee, K. Koike, T. Nikaido. Polyhydroxypregnane glycosides from the flowers of Dregea volubilis. Phytochemistry, 61, 383-388 (2002).

Y. Zhang, M. Xu, D. Wang, H. Zhu, C. Yang. Application of c-3,11,12,20-tetra-substituted c-21 steroid derivatives and their pharmaceutical composition in preparation of drugs for treating epilepsy.China Patent CN102924554A; (2013), 1-27.

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Published

13-07-2020

Issue

Section

Natural Products