Hepatoprotective effects of phenolic glycosides from the methanol extract of Physalis angulata

Hoang Le Tuan Anh; Duong Thi Dung; Do Thanh Tuan; Trieu Quy Hung; Pham Thi Hai Yen; Tran Hong Quang; Nguyen Xuan Nhiem; Chau Van Minh; Duong Thi Hai Yen; Phan Van Kiem

doi:10.15625/0866-708X/55/2/8527

Hepatoprotective effects of phenolic glycosides from the methanol extract of Physalis angulata

Hoang Le Tuan Anh, Duong Thi Dung, Do Thanh Tuan, Trieu Quy Hung, Pham Thi Hai Yen, Tran Hong Quang, Nguyen Xuan Nhiem, Chau Van Minh, Duong Thi Hai Yen, Phan Van Kiem

Author affiliations

Authors

Hoang Le Tuan Anh Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Duong Thi Dung Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Do Thanh Tuan Thai Binh Medical University, 373, Li Bon, Thai Binh, Viet Nam
Trieu Quy Hung Faculty of Natural Sciences, Hung Vuong University, Nguyen Tat Thanh, Viet Tri, Phu Tho, Viet Nam
Pham Thi Hai Yen Thanh Hoa Sports and Physical Education College, 24 Hoang Van Thu, Ngoc Trao, Thanh Hoa, Viet Nam
Tran Hong Quang Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Nguyen Xuan Nhiem Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Chau Van Minh Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Duong Thi Hai Yen Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Phan Van Kiem Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam

DOI:

https://doi.org/10.15625/0866-708X/55/2/8527

Keywords:

Physalis angulata, phenolic glycoside, hepatoprotective effect

Abstract

By various chromatographic separations, four phenolic glycosides, methyl salicylate 2-O-triglycoside (1), icariside E₅ (2), quercetin 3-O-rutinoside (3), and isorhamnetin 3-O-rutinoside (4) were isolated from the methanol extract of the whole plant of Physalis angulata. Their structures were determined by 1D-, 2D-NMR spectroscopic analyses and in comparison with the reported data. Compounds 3 exhibited significantly hepatoprotective activity with an EC₅₀ value of 17.08 µg/mL. This is the first report of 1-4 from Physalis angulata.

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Published

17-04-2017

How to Cite

[1]

H. L. Tuan Anh, “Hepatoprotective effects of phenolic glycosides from the methanol extract of Physalis angulata”, Vietnam J. Sci. Technol., vol. 55, no. 2, pp. 161–167, Apr. 2017.

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Issue

Vol. 55 No. 2 (2017)

Section

Natural Products

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