A preliminary investigation of occurrence of pharmaceuticals and personal care products in total suspended particulate matter in Ha Noi, Viet Nam

Nguyen Hai Doan, Kiwao Kadokami, Vu Le Minh, Hanh Thi Duong
Author affiliations

Authors

  • Nguyen Hai Doan Graduate School of Global Environmental Studies, Sophia University, Kioicho 7-1, Chiyoda-ku, Tokyo 102-8554, Japan
  • Kiwao Kadokami Institute of Environmental Science and Technology, The University of Kitakyushu, 1-1 Hibikino, Wakamatsu, Kitakyushu, Fukuoka, 808-0135, Japan
  • Vu Le Minh Institute of Science and Technology for Energy and Environment, Viet Nam Academy of Science and Technology, No. 18 Hoang Quoc Viet street, Cau Giay district, Ha Noi city, Viet Nam
  • Hanh Thi Duong Institute of Science and Technology for Energy and Environment, Viet Nam Academy of Science and Technology, No. 18 Hoang Quoc Viet street, Cau Giay district, Ha Noi city, Viet Nam

DOI:

https://doi.org/10.15625/2525-2518/16481

Keywords:

Target screening analysis, ,LC-QTOF-MS-SWATH, PPCP, air particle

Abstract

Air pollution has become a serious environmental issue in Viet Nam, particularly in large cities. There is little information regarding the presence of pharmaceuticals and personal care products (PPCPs) in suspended particulate matter in Ha Noi, Viet Nam. The present study screened 163 PPCPs from 12 total suspended particulate matter (TSP) samples collected in Ha Noi using a novel analytical method, the liquid chromatography-mass spectrometry-quadrupole time of flight-Sequential Window Acquisition of All Theoretical Fragment Ion Spectra method (LC-QTOF-MS-SWATH). We identified and quantified 6 of the 163 PPCPs. All of the 6 PPCPs were detected for the first time in TSP. The total concentration ranged from 37.3 to 401.0 pg m-3 (median: 143 pg m-3). The number of PPCPs detected per sample ranged from 1 to 5 (median: 3), and their figure found was higher in the nighttime than that of the daytime.

Downloads

Download data is not yet available.

References

Do D. H., Walgraeve C., Amare A. N., Barai K. R., Parao A. E., Demeestere K., van Langenhove H. - Airborne volatile organic compounds in urban and industrial locations in four developing countries, Atmospheric Environment 119 (2015) 330-338.

Trinh T. T., Nguyen T. D. H., Nguyen T. A. T., Trinh T. T. - Research on Effects of Temperature Inversions to Concentration of Particulate Metter (PM2.5) in the Atmosphere in Ha Noi VNU Journal of Science: Earth and Environmental Sciences 34 (2018).

Wang Z., Walker G. W., Muir D. C. G., Nagatani-Yoshida K. - Toward a Global Understanding of Chemical Pollution: A First Comprehensive Analysis of National and Regional Chemical Inventories, Environmental Science & Technology 54 (2020) 2575-2584.

Tuyen L. H., Tue N. M., Suzuki G., Misaki K., Viet P. H., Takahashi S., Tanabe S. - Aryl hydrocarbon receptor mediated activities in road dust from a metropolitan area, Hanoi—Vietnam: Contribution of polycyclic aromatic hydrocarbons (PAHs) and human risk assessment, Science of The Total Environment 491-492 (2014) 246-254.

Anh H. Q., Tomioka K., Tue N. M., Tuyen L. H., Chi N. K., Minh T. B., Viet P. H., Takahashi S. - A preliminary investigation of 942 organic micro-pollutants in the atmosphere in waste processing and urban areas, northern Vietnam: Levels, potential sources, and risk assessment, Ecotoxicology and Environmental Safety 167 (2019) 354-364.

Wang W., Wang Y., Zhang R., Wang S., Wei C., Chaemfa C., Li J., Zhang G., Yu K. - Seasonal characteristics and current sources of OCPs and PCBs and enantiomeric signatures of chiral OCPs in the atmosphere of Vietnam, Science of The Total Environment 542 (2016) 777-786.

Trinh M. M., Tsai C. L., Hien T. T., Thuan N. T., Chi K. H., Lien C. G., Chang M. B. - Atmospheric concentrations and gas-particle partitioning of PCDD/Fs and dioxin-like PCBs around Hochiminh city, Chemosphere 202 (2018) 246-254.

Tue N. M., Takahashi S., Suzuki G., Isobe T., Viet P. H., Kobara Y., Seike N., Zhang G., Sudaryanto A., Tanabe S. - Contamination of indoor dust and air by polychlorinated biphenyls and brominated flame retardants and relevance of non-dietary exposure in Vietnamese informal e-waste recycling sites, Environment International 51 (2013) 160-167.

Tran T. M., Le H. T., Vu N. D., Minh Dang G. H., Minh T. B., Kannan K. - Cyclic and linear siloxanes in indoor air from several northern cities in Vietnam: Levels, spatial distribution and human exposure, Chemosphere 184 (2017) 1117-1124.

Duong H. T., Kadokami K., Trinh H. T., Phan T. Q., Le G. T., Nguyen D. T., Nguyen T. T., Nguyen D. T. - Target screening analysis of 970 semi-volatile organic compounds adsorbed on atmospheric particulate matter in Hanoi, Vietnam, Chemosphere 219 (2019) 784-795.

Melvin S. D., Leusch F. D. L. - Removal of trace organic contaminants from domestic wastewater: A meta-analysis comparison of sewage treatment technologies, Environment International 92 (2016) 183-188.

Fatehifar M., Borghei S. M., Ekhlasi nia A. - Application of moving bed biofilm reactor in the removal of pharmaceutical compounds (diclofenac and ibuprofen), Journal of Environmental Chemical Engineering 6 (2018) 5530-5535.

Kallenborn R., Gatermann R., Planting S., Rimkus G. G., Lund M., Schlabach M., Burkow I. C. - Gas chromatographic determination of synthetic musk compounds in Norwegian air samples, Journal of Chromatography A 846 (1999) 295-306.

Peck A. M., Hornbuckle K. C. - Synthetic musk fragrances in urban and rural air of Iowa and the Great Lakes, Atmospheric Environment 40 (2006) 6101-6111.

Ramírez N., Marcé R. M., Borrull F. - Development of a stir bar sorptive extraction and thermal desorption–gas chromatography–mass spectrometry method for determining synthetic musks in water samples, Journal of Chromatography A 1218 (2011) 156-161.

Medeiros P. M., Simoneit B. R. T. - Gas chromatography coupled to mass spectrometry for analyses of organic compounds and biomarkers as tracers for geological, environmental, and forensic research, Journal of Separation Science 30 (2007) 1516-1536.

Aceveş M., Grimalt J. O. - Large and small particle size screening of organic compounds in urban air, Atmospheric Environment. Part B. Urban Atmosphere 27 (1993) 251-263.

Kadokami K., Ueno D. - Comprehensive Target Analysis for 484 Organic Micropollutants in Environmental Waters by the Combination of Tandem Solid-Phase Extraction and Quadrupole Time-of-Flight Mass Spectrometry with Sequential Window Acquisition of All Theoretical Fragment-Ion Spectra Acquisition, Analytical Chemistry 91 (2019) 7749-7755.

Ferrer I., Thurman E. M. - Multi-residue method for the analysis of 101 pesticides and their degradates in food and water samples by liquid chromatography/time-of-flight mass spectrometry, Journal of Chromatography A 1175 (2007) 24-37.

Lee H. J., Kadokami K., Oh J. E. - Occurrences of microorganic pollutants in the Kumho River by a comprehensive target analysis using LC-Q/TOF-MS with sequential window acquisition of all theoretical fragment ion spectra (SWATH), Science of The Total Environment 713 (2020) 136508.

Doan N. H., Duong H. T., Trinh H. T., Tanaka Y., Kadokami K. - Comprehensive study of insecticides in atmospheric particulate matter in Hanoi, Vietnam: Occurrences and human risk assessment, Chemosphere 262 (2021) 128028.

Cedron V. P., Weiner A. M. J., Vera M., Sanchez L. - Acetaminophen affects the survivor, pigmentation and development of craniofacial structures in zebrafish (Danio rerio) embryos, Biochemical Pharmacology 174 (2020) 113816.

Quesada H. B., Baptista A. T. A., Cusioli L. F., Seibert D., de Oliveira Bezerra C., Bergamasco R. - Surface water pollution by pharmaceuticals and an alternative of removal by low-cost adsorbents: A review, Chemosphere 222 (2019) 766-780.

Spongberg A. L., Witter J. D., Acuña J., Vargas J., Murillo M., Umaña G., Gómez E., Perez G. - Reconnaissance of selected PPCP compounds in Costa Rican surface waters, Water Research 45 (2011) 6709-6717.

Burns E. E., Carter L. J., Kolpin D. W., Thomas-Oates J., Boxall A. B. A. - Temporal and spatial variation in pharmaceutical concentrations in an urban river system, Water Research 137 (2018) 72-85.

Calafat A. M., Wong L. Y., Ye X., Reidy J. A., Needham L. L. - Concentrations of the Sunscreen Agent Benzophenone-3 in Residents of the United States: National Health and Nutrition Examination Survey 2003–2004 116 (2008) 893-897.

Suzuki T., Kitamura S., Khota R., Sugihara K., Fujimoto N., Ohta S. - Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens, Toxicology and Applied Pharmacology 203 (2005) 9-17.

Mao F., He Y., Gin K. Y. H. - Occurrence and fate of benzophenone-type UV filters in aquatic environments: a review, Environmental Science: Water Research & Technology 5 (2019) 209-223.

Mínguez-Alarcón L., Chiu Y. H., Nassan F. L., Williams P. L., Petrozza J., Ford J. B., Calafat A. M., Hauser R., Chavarro J. E. - Urinary concentrations of benzophenone-3 and reproductive outcomes among women undergoing infertility treatment with assisted reproductive technologies, Science of the total Environment 678 (2019) 390-398.

Damiani E., Carloni P., Biondi C., Greci L. - Increased oxidative modification of albumin when illuminated in vitro in the presence of a common sunscreen ingredient: protection by nitroxide radicals, Free Radical Biology and Medicine 28 (2000) 193-201.

Scalia S., Simeoni S., Barbieri A., Sostero S. - Influence of hydroxypropyl-β-cyclodextrin on photo-induced free radical production by the sunscreen agent, butyl-methoxydibenzoylmethane 54 (2002) 1553-1558.

Schwack W., Rudolph T. - Photochemistry of dibenzoyl methane UVA filters Part 1, Journal of Photochemistry and Photobiology B: Biology 28 (1995) 229-234.

Chatelain E., Gabard B. - Photostabilization of Butyl methoxydibenzoylmethane (Avobenzone) and Ethylhexyl methoxycinnamate by Bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a New UV Broadband Filter 74 (2001) 401-406.

Tsui M. M. P., Leung H. W., Lam P. K. S., Murphy M. B. - Seasonal occurrence, removal efficiencies and preliminary risk assessment of multiple classes of organic UV filters in wastewater treatment plants, Water Research 53 (2014) 58-67.

Downloads

Published

18-06-2024

How to Cite

[1]
N. Hai Doan, K. Kadokami, V. Le Minh, and H. T. Duong, “A preliminary investigation of occurrence of pharmaceuticals and personal care products in total suspended particulate matter in Ha Noi, Viet Nam”, Vietnam J. Sci. Technol., vol. 62, no. 3, pp. 530–538, Jun. 2024.

Issue

Section

Environment