LIMONOIDS FROM FRUITS OF Melia dubia Cav. IN VIETNAM
Keywords:Melia dubia, limonoid, 21α-O-methylmelianodiol, 21β-O-methylmelianodiol and (21S, 23R, 24R)-21, 23-epoxy-24-hydroxy-21β-methoxytirucalla-7, 25-dien-3-one.
AbstractA phytochemical study on fruits of Melia dubia Cav. collected in Nghe An province led to the isolation of three secondary metabolites, including 21α-O-methylmelianodiol (1), 21β-O-methylmelianodiol (2) and (21S,23R,24R)-21,23-epoxy-24-hydroxy-21β-methoxytirucalla-7,25-dien-3-one (3). The chemical structures of these compounds were determined on the basis of 1D, 2D NMR, UV, IR and MS analytical results and comparison with reported data. All three compounds (1–3) were isolated from this plant for the first time.
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