LIMONOIDS FROM FRUITS OF Melia dubia Cav. IN VIETNAM

Authors

  • Hieu Trung Tran
  • Tuan Ngoc Nguyen
  • Tien Quyet Nguyen
  • Thanh Tan Nguyen
  • Hoang Dinh Vu
  • Trinh Thi Nu Nguyen
  • Thang Dinh Tran

DOI:

https://doi.org/10.15625/2525-2518/59/4/16012

Keywords:

Melia dubia, limonoid, 21α-O-methylmelianodiol, 21β-O-methylmelianodiol and (21S, 23R, 24R)-21, 23-epoxy-24-hydroxy-21β-methoxytirucalla-7, 25-dien-3-one.

Abstract

A phytochemical study on fruits of Melia dubia Cav. collected in Nghe An province led to the isolation of three secondary metabolites, including 21α-O-methylmelianodiol (1), 21β-O-methylmelianodiol (2) and (21S,23R,24R)-21,23-epoxy-24-hydroxy-21β-methoxytirucalla-7,25-dien-3-one (3). The chemical structures of these compounds were determined on the basis of 1D, 2D NMR, UV, IR and MS analytical results and comparison with reported data. All three compounds (13) were isolated from this plant for the first time.

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