STUDY ON MIXING ANTI-A MONOCLONAL ANTIBODY AND ANTI-B MONOCLONAL ANTIBODY TO MAKE ANTI-AB SAVE AS ABO BLOOD GROUPING REAGENT

Authors

  • Nguyen Thi Trung VAST
  • Truong Nam Hai

DOI:

https://doi.org/10.15625/2525-2518/56/1/9372

Keywords:

ABO blood group system, ABO blood grouping reagent

Abstract

So, it needs to balance the ratio of anti-A monoclonal antibody and anti-B monoclonal antibody  in the mixing so that the possibility of agglutination is the best. In this paper, anti-A monoclonal antibody (titer is 1/256) and anti-B monoclonal antibody (titer is 1/256) was used. The best results were obtained at one volume anti A monoclonal antibody is mixed one volume anti-B monoclonal antibody. The anti-A,B antibody titer was 1/128 for red blood group A and it was 1/128 for red blood group B. The intensity of agglutination reached  3+ for both red blood group A and B.

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Author Biography

Nguyen Thi Trung, VAST

Institute of BiotechnologySo, it needs to balance the ratio of anti-A monoclonal antibody and anti-B monoclonal antibody  in the mixing so that the possibility of agglutination is the best. In this paper, anti-A monoclonal antibody (titer is 1/256) and anti-B monoclonal antibody (titer is 1/256) was used. The best results were obtained at one volume anti A monoclonal antibody is mixed one volume anti-B monoclonal antibody. The anti-A,B antibody titer was 1/128 for red blood group A and it was 1/128 for red blood group B. The intensity of agglutination reached  3+ for both red blood group A and B.

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Published

2018-01-30

Issue

Section

Natural Products