Evaluation of Sterculia foetida L. gum as natural based disintegrating excipient
Author affiliations
DOI:
https://doi.org/10.15625/2525-2518/57/3/13323Keywords:
Sterculia foetida L. gum, controlled release excipient, HPMC E15, in vitro release testing.Abstract
Therefore, the physicochemical properties of Sterculia foetida L. gum, including solubility, scanning electron micrographs, melting point, swelling index, pH, viscosity, loss on drying were determined. Furthermore, compressed tablets were successfully prepared for in vitro studies at many different particle sizes, concentrations of gum, rotational speeds and media in order to evaluate the effects of these parameters on the rate of drug release. Besides, SFG tablets were compared with the tablets prepared with Hydroxymethylcellulose E15. The findings indicated that Sterculia foetida L. gum exhibited an excellent potential in managed release dosage forms.
Downloads
References
Sanjib B., Uttam K. S., Dipesh S., Ghanshyam S., Amit R. - Review on natural gum and mucilage and their application as excipient, Journal of Applied Pharmaceutical Research 5 (4) (2017) 13-21.
Shaikh M. D., Dhotre R.S. and Kare M. A. - Pharmacognostical and Phytochemical Evaluation of Sterculia Foetida L. Stem Bark, International Journal of Scientific Research in Science and Technology 3 (8) (2017) 1069-1072.
Chivate A. A., Poddar S. S., Abdul S. and Savant G. - Evaluation of Sterculia foetida gum as controlled release excipient, AAPS Pharm Sci Tech 9 (1) (2008) 197-204.
Namdeo T. B., Vidya R. I. and Sushilkumar S. P. - Sustained-release from Layered matrix system comprising rice bran wax and Sterculia foetida gum, International Journal of Pharmtech Research 2 (1) (2010) 989-1005.
Paresh A. P., Sushikumar S. P., Madhabhai M. P., Balkrishna K. P. - Ophthalmic minitablet with natural polymer: Sterculia foetida gum, Der Pharmacia Lettre 2 (1) (2010) 467-74.
Dixit G.R., Chavhan J.I., Kanchan P. U., Sushant M. - Formualtion and characterization of mucoadhesive buccal film of ranitidine hydrochloride using Sterculia foetida gum as polymer, Asian Journal of Pharmaceutical and Clinical Research 8 (3) (2015) 68-71.
Nayak R. K., Narayana Swammny V. B., Senthil A., Mahalaxmi R. - An In-Vitro Evaluation of Mangifera Indica Gum As A Potential Excipients for Oral Controlled Released Matrix Tablet, Pharmacologyonline 2 (2011) 360- 391.
United States Pharmacopeia 26, Apparatus for Paddle Method (Apparatus 2) (2003).
Cerf D. L., Irinei F., Muller G. - Carbohydrate Polymer 13 (4) (1990) 351–458.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Vietnam Journal of Sciences and Technology (VJST) is an open access and peer-reviewed journal. All academic publications could be made free to read and downloaded for everyone. In addition, articles are published under term of the Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA) Licence which permits use, distribution and reproduction in any medium, provided the original work is properly cited & ShareAlike terms followed.
Copyright on any research article published in VJST is retained by the respective author(s), without restrictions. Authors grant VAST Journals System a license to publish the article and identify itself as the original publisher. Upon author(s) by giving permission to VJST either via VJST journal portal or other channel to publish their research work in VJST agrees to all the terms and conditions of https://creativecommons.org/licenses/by-sa/4.0/ License and terms & condition set by VJST.
Authors have the responsibility of to secure all necessary copyright permissions for the use of 3rd-party materials in their manuscript.
Vietnam Journal of Science and Technology (VJST) is pleased to notice: