EVALUATION OF STERCULIA FOETIDA L. GUM AS NATURAL BASED CONTROLLED RELEASE EXCIPIENT
Keywords:Sterculia foetida L. gum, controlled release excipient, HPMC E15, in vitro release testing.
Therefore, the physicochemical properties of Sterculia foetida L. gum, including solubility, scanning electron micrographs, melting point, swelling index, pH, viscosity, loss on drying were determined. Furthermore, compressed tablets were successfully prepared for in vitro studies at many different particle sizes, concentrations of gum, rotational speeds and media in order to evaluate the effects of these parameters on the rate of drug release. Besides, SFG tablets were compared with the tablets prepared with Hydroxymethylcellulose E15. The findings indicated that Sterculia foetida L. gum exhibited an excellent potential in managed release dosage forms.
Sanjib B., Uttam K. S., Dipesh S., Ghanshyam S., Amit R. - Review on natural gum and mucilage and their application as excipient, Journal of Applied Pharmaceutical Research 5 (4) (2017) 13-21.
Shaikh M. D., Dhotre R.S. and Kare M. A. - Pharmacognostical and Phytochemical Evaluation of Sterculia Foetida L. Stem Bark, International Journal of Scientific Research in Science and Technology 3 (8) (2017) 1069-1072.
Chivate A. A., Poddar S. S., Abdul S. and Savant G. - Evaluation of Sterculia foetida gum as controlled release excipient, AAPS Pharm Sci Tech 9 (1) (2008) 197-204.
Namdeo T. B., Vidya R. I. and Sushilkumar S. P. - Sustained-release from Layered matrix system comprising rice bran wax and Sterculia foetida gum, International Journal of Pharmtech Research 2 (1) (2010) 989-1005.
Paresh A. P., Sushikumar S. P., Madhabhai M. P., Balkrishna K. P. - Ophthalmic minitablet with natural polymer: Sterculia foetida gum, Der Pharmacia Lettre 2 (1) (2010) 467-74.
Dixit G.R., Chavhan J.I., Kanchan P. U., Sushant M. - Formualtion and characterization of mucoadhesive buccal film of ranitidine hydrochloride using Sterculia foetida gum as polymer, Asian Journal of Pharmaceutical and Clinical Research 8 (3) (2015) 68-71.
Nayak R. K., Narayana Swammny V. B., Senthil A., Mahalaxmi R. - An In-Vitro Evaluation of Mangifera Indica Gum As A Potential Excipients for Oral Controlled Released Matrix Tablet, Pharmacologyonline 2 (2011) 360- 391.
United States Pharmacopeia 26, Apparatus for Paddle Method (Apparatus 2) (2003).
Cerf D. L., Irinei F., Muller G. - Carbohydrate Polymer 13 (4) (1990) 351–458.
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