CHEMICAL AND PHARMACOLOGICAL EVALUATION OF MANGLICOLOUS LICHEN GRAPHIS AJAREKARII PATW. & C. R. KULK.

Authors

  • Polimati Haritha
  • Sunil Kumar Patnaik
  • Vinay Bharadwaj Tatipamula Assistant Professor, Pharmaceutical Chemistry Department, KL College of Pharmacy, K L Deemed to be University, Vaddeswaram – 522 502, Guntur, Andhra Pradesh, India http://orcid.org/0000-0002-9376-1911

DOI:

https://doi.org/10.15625/2525-2518/57/3/13679

Keywords:

manglicolous lichen, antioxidant, cancer, Sulforhodamine B assay

Abstract

The chemical examination of ethanolic extract of manglicolous lichen Graphis ajarekarii (Ga-Et) resulted in isolation of three known metabolites – chiodectonic acid (1), graphenone (2) and graphisquinone (3). All the isolates (1-3) and Ga-Et were screened against DPPH and superoxide free radicals, six different cancer cell lines and one normal human cell line (NHME). This work is the first report of antioxidant and cytotoxicity studies on the isolated metabolites (1-3).

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Author Biography

Vinay Bharadwaj Tatipamula, Assistant Professor, Pharmaceutical Chemistry Department, KL College of Pharmacy, K L Deemed to be University, Vaddeswaram – 522 502, Guntur, Andhra Pradesh, India

Pharmaceutical Chemistry Department and Assistant Professor

References

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Published

2019-06-04

Issue

Section

Natural Products