Silver nanoparticles synthesized using S. nervosum leaf extract, and their  antibacterial and antifungal activity  : Cong Hong Hanh1, *, Pham Sy Hieu1, Nguyen Hong Nhung1, Tran Que Chi1, Tran Thi Huong1, Pham Duy Khanh1, Pham Thi Gam2, Nguyen Van Phuong3, Phan Thi Thanh Nga4, Hoang Hien Y5, 6, Dao My Uyen5, 6, Hoang Anh Son1, *

Hong Hanh Cong; Pham Sy Hieu; Nguyen Hong Nhung; Tran Que Chi; Tran Thi Huong; Pham Duy Khanh; Pham Thi Gam; Nguyen Van Phuong; Phan Thi Thanh Nga; Hoang Hien Y; Dao My Uyen; Hoang Anh Son

doi:10.15625/2525-2518/19366

Author affiliations

Authors

Hong Hanh Cong Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam https://orcid.org/0000-0002-9638-6168
Pham Sy Hieu Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam
Nguyen Hong Nhung Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam
Tran Que Chi Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam
Tran Thi Huong Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam
Pham Duy Khanh Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam
Pham Thi Gam Faculty of Pharmacy, Ha Noi University of Business and Technology, Vinh Tuy ward, Ha Noi, Viet Nam
Nguyen Van Phuong University of Science and Technology of Hanoi, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam
Phan Thi Thanh Nga Faculty of Chemical Engineering, Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet, Dien Hong ward, Ho Chi Minh, Viet Nam
Hoang Hien Y Center for Advanced Chemistry, Institute of Research & Development, Duy Tan University, Da Nang, Viet Nam
Dao My Uyen Faculty of Natural Sciences, Duy Tan University, Da Nang, Viet Nam
Hoang Anh Son Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do ward, Ha Noi, Viet Nam

DOI:

https://doi.org/10.15625/2525-2518/19366

Keywords:

Green synthesis, AgNPs, S. nervosum, antibacterial activity, antifungal activity

Abstract

In this study, the green synthesis of silver nanoparticles (AgNPs) was performed using S.nervosum leaf extract, and their physicochemical characterization was also studied. The characteristic surface plasmon resonance peak observed in the visible region at 435 nm is consistent with previous reports of silver nanoparticle formation. The synthesized AgNPs were also characterized by SEM, TEM, XRD, and FTIR, which revealed their nearly spherical shape, with a diameter mainly in the 10 - 30 nm range. The antimicrobial activity of AgNPs was studied using the agar well diffusion method on four clinically significant pathogenic microorganisms (P. aeruginosa ATCC 27853; E. coli ATCC 35218, S. aureus ATCC 12493; S. aureus Mastitis isolate). The results showed that the green-synthesized AgNPs exhibited antimicrobial activity at most studied concentrations, including the antibacterial effect against the S. Aureus (Mastitis isolate) strain, which was found to be resistant to Tetracycline at 100 µg/L. The antifungal activity of these nanoparticles was also studied on Colletotrichum gloeopsoriodes by colony formation assay. The green synthesis of AgNPs was successfully conducted for the first time using the aqueous extract of S. nervosum. The results of this study indicate that the silver nanoparticles have potential applications as antibacterial and antifungal agents.

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