Structure elucidation and cytotoxic activity of attenuatoside B-1, planciside A, and culcitoside C2 from the starfish Acanthaster planci

Le Thi Vien; Tran Thi Hong Hanh; Phan Thi Thanh Huong; Do Thi Thao; Nguyen Van Thanh; Nguyen Xuan Cuong; Nguyen Hoai Nam

doi:10.15625/2525-2518/56/1/9207

Structure elucidation and cytotoxic activity of attenuatoside B-1, planciside A, and culcitoside C2 from the starfish Acanthaster planci

Le Thi Vien, Tran Thi Hong Hanh, Phan Thi Thanh Huong, Do Thi Thao, Nguyen Van Thanh, Nguyen Xuan Cuong, Nguyen Hoai Nam

Author affiliations

Authors

Le Thi Vien Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Tran Thi Hong Hanh Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Phan Thi Thanh Huong Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Do Thi Thao Institute of Biotechnology, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Nguyen Van Thanh Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Nguyen Xuan Cuong Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam
Nguyen Hoai Nam Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam

DOI:

https://doi.org/10.15625/2525-2518/56/1/9207

Keywords:

Acanthaster planci, starfish, steroid glycoside, cytotoxic activity

Abstract

Detailed analysis of the 1D and 2D NMR data and comparison with the reported values, the structures of attenuatoside B-1 (1), planciside A (2), and culcitoside C₂ (3) from starfish Acanthaster planci were clearly elucidated. Culcitoside C₂ (3) showed weak cytotoxic activity against five human cancer cell lines including HepG2, KB, LNCaP, MCF7, and SK-Mel2.

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Published

30-01-2018

How to Cite

[1]

L. T. Vien, “Structure elucidation and cytotoxic activity of attenuatoside B-1, planciside A, and culcitoside C2 from the starfish Acanthaster planci”, Vietnam J. Sci. Technol., vol. 56, no. 1, pp. 1–6, Jan. 2018.

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Issue

Vol. 56 No. 1 (2018)

Section

Natural Products

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