Chemical constituents from the leaves of Achornea rugosa (Lour.) Müll. Arg. (Euphorbiaceae)

Pham Van Huyen, Nguyen Thi Thu Hien, Nguyen Huu Huong Duyen, Nguyen Thi Dieu Thuan, Nguyen Huu Toan Phan
Author affiliations

Authors

  • Pham Van Huyen Tay Nguyen Institute for Scientific Research, VAST, 116 Xo Viet Nghe Tinh, Da Lat, Viet Nam
  • Nguyen Thi Thu Hien Tay Nguyen Institute for Scientific Research, VAST, 116 Xo Viet Nghe Tinh, Da Lat, Viet Nam
  • Nguyen Huu Huong Duyen Tay Nguyen Institute for Scientific Research, VAST, 116 Xo Viet Nghe Tinh, Da Lat, Viet Nam
  • Nguyen Thi Dieu Thuan Tay Nguyen Institute for Scientific Research
  • Nguyen Huu Toan Phan Tay Nguyen Institute for Scientific Research, VAST, 116 Xo Viet Nghe Tinh, Da Lat, Viet Nam https://orcid.org/0000-0001-7390-608X

DOI:

https://doi.org/10.15625/2525-2518/15442

Keywords:

Alchornea rugosa, 3β-friedelanol, friedelan-3-one, methyl syringate, isovitexin, rhoifolin

Abstract

Alchornea is a genus of plants in the family Euphorbiaceae. It is widely distributed in tropical and subtropical regions of Africa, South Asia, Australia, and Latin America. Many species of the genus Alchornea have been used in traditional medicine in some countries around the world. Therefore, there have been many studies focusing on the chemical composition and biological activities of some species of the genus Alchornea. In the research project on the chemical composition of 4 species of Alchornea distributed in Viet Nam, we have reported compounds isolated from 3 species A. tiliaefolia, A. annamatica, and A. trewioides. Alchornea rugosa grows wild throughout Viet Nam and has been used in traditional medicine, but little is known about its chemical composition. From the leaves of species A. rugosa collected in Me Linh district, Ha Noi city, Viet Nam, five compounds including 3β-friedelanol (1), friedelan-3-one (2), methyl syringate (3), isovitexin (4), and rhoifolin (5) has been isolated from the methanol extract from its leaves by different chromatographic techniques. Their chemical structures were determined based on 1D and 2D NMR spectroscopy and mass spectrometry analysis and comparison with reference material. This is the first report on the isolation of these compounds from A. rugosa.

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Published

21-06-2022

How to Cite

[1]
P. V. Huyen, N. T. T. Hien, N. H. H. Duyen, N. T. D. Thuan, and N. H. T. Phan, “Chemical constituents from the leaves of Achornea rugosa (Lour.) Müll. Arg. (Euphorbiaceae)”, Vietnam J. Sci. Technol., vol. 60, no. 3, pp. 343–349, Jun. 2022.

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Natural Products

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