Evaluation of biological activities of some seaweed and seagrass species in the coastal area of Vietnam

Tran Thi Hong Ha; Le Mai Huong; Le Huu Cuong; Nguyen Dinh Tuan; Hoang Kim Chi; Tran Thi Nhu Hang; Do Huu Nghi; Dang Thi Phuong Ly; Andrei B. Imbs; Pham Quoc Long

doi:10.15625/1859-3097/19/3/14060

Author affiliations

Authors

Tran Thi Hong Ha Institute of Natural Products Chemistry, VAST, Vietnam
Le Mai Huong Institute of Natural Products Chemistry, VAST, Vietnam
Le Huu Cuong Institute of Natural Products Chemistry, VAST, Vietnam
Nguyen Dinh Tuan Institute of Natural Products Chemistry, VAST, Vietnam
Hoang Kim Chi Institute of Natural Products Chemistry, VAST, Vietnam Graduate University of Science and Technology, VAST, Vietnam
Tran Thi Nhu Hang Institute of Natural Products Chemistry, VAST, Vietnam
Do Huu Nghi Institute of Natural Products Chemistry, VAST, Vietnam
Dang Thi Phuong Ly Institute of Natural Products Chemistry, VAST, Vietnam
Andrei B. Imbs Institute of Marine Biology, FEB RAS, Russia
Pham Quoc Long Institute of Natural Products Chemistry, VAST, Vietnam

DOI:

https://doi.org/10.15625/1859-3097/19/3/14060

Keywords:

Antioxidant, antimicrobial, cytotoxicity, seagrass, seaweed, Vietnam Sea.

Abstract

Although seaweeds and seagrasses have been used for food and traditional medicine for centuries, merely a small amount of them is exploited and used. Positive biological activities of seaweed and seagrass products on humans, animals and plants have also been recorded for a long time. Vietnam is a tropical country with 3,260 km long coastline and about 350 species of seaweeds, including 60 widely used species. In this study, 57 seaweed and seagrass samples were extracted using CHCl₃/MeOH solvent systems and their crude extracts were tested for selected biological actives, including antimicrobial, antioxidant activities and cytotoxicity. The results revealed that 13 out of 57 extracts (accounting for 24.07%) were cytotoxic to one of the two tested cancer cell lines (Hepatocellular carcinoma cell line Hep-G2 and human lung adenocarcinoma cell line LU-1), and 4 extracts (accounting for 7.4%) were cytotoxic to both cancer cell lines. In antimicrobial activity assay, 18 of all 57 extracts (accounting for 37.5%) were capable of inhibiting 1 to 2 test microorganisms and 16 extracts (accounting for 33.33%) inhibited at least 3 test microorganisms. There were solely 1 extract (accounting for 1.85%) of the 57 extracts performing antioxidant activity in DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay.

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