Investigation of antioxidant activity of <i>Zoanthus vietnamensis</i>’s crude extract and dichloromethane extract

Bao Vy Phan; Khanh Hy Le Ho; Phuong Anh Nguyen; Thi Thiet Doan; Xuan Ky Pham; Viet Ha Dao

doi:10.15625/1859-3097/18293

Author affiliations

Authors

Phan Bao Vy Institute of Oceanography, VAST, Vietnam https://orcid.org/0009-0001-6768-6313
Le Ho Khanh Hy Institute of Oceanography, VAST, Vietnam
Nguyen Phuong Anh Institute of Oceanography, VAST, Vietnam
Doan Thi Thiet Institute of Oceanography, VAST, Vietnam
Pham Xuan Ky Institute of Oceanography, VAST, Vietnam
Dao Viet Ha Institute of Oceanography, VAST, Vietnam

DOI:

https://doi.org/10.15625/1859-3097/18293

Keywords:

Antioxidant activity, ethanol crude extract, dichloromethane extract, Zoanthus vietnamensis.

Abstract

Zoanthid is a potential natural resource with many biological activities, such as antioxidant, antiviral, anti-inflammatory, and cytotoxic activity. Therefore, this study aimed to evaluate the antioxidant activity of 70% ethanol crude extract and dichloromethane fraction from Zoanthus vietnamensis. The total polyphenol content of ethanol and dichloromethane extracts were 19.36 ± 1.37 and 24.95 ± 0.63 mg GAE/g extract, respectively. The DPPH free radical scavenging capacity increased slightly from low to high concentration. The IC50 values reached 9.974 µg/mL and 6.424 µg/mL for ethanol crude and dichloromethane extract. The potassium ferricyanide-reducing power assay result was meager, and the optical density value ranges from 0.015 to 0.105.

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References

Daly, M., Brugler, M. R., Cartwright, P., Collins, A. G., Dawson, M. N., Fautin, D. G., France, S. C., Mcfadden, C. S., Opresko, D. M., Rodriguez, E., Romano, S. L., and Stake, J. L., 2007. The phylum Cnidaria: A review of phylogenetic patterns and diversity 300 years after Linnaeus. Zootaxa, 1668, 127–182.

Roy, P. K., Maarisit, W., Roy, M. C., Taira, J., and Ueda, K., 2012. Five new diterpenoids from an Okinawan soft coral, Cespitularia sp. Marine Drugs, 10(12), 2741–2748.

Radjasa, O. K., Vaske, Y. M., Navarro, G., Vervoort, H. C., Tenney, K., Linington, R. G., and Crews, P., 2011. Highlights of marine invertebrate-derived biosynthetic products: Their biomedical potential and possible production by microbial associants. Bioorganic & medicinal chemistry, 19(22), 6658–6674.

Blunt, J. W., Copp, B. R., Keyzers, R. A., Munro, M. H., and Prinsep, M. R., 2014. Marine natural products. Natural product reports, 31(2), 160–258.

Cuong, D. X., Boi, V. N., Nhan, T. K. T., Dong, D. H., Quang, T. M., Tram, P. T. K., and Tuyen, D. T. T., 2019. Polyphenol content, phytochemistry compositions and antioxidant activity of different extracts from marine sponge Aaptos suberitoides grown in Nhatrang Bay, Vietnam. Pharmacy and Pharmaceutical Sciences, 11(9), 1–7.

Choudhari, S. K., Chaudhary, M., Gadbail, A. R., Sharma, A., and Tekade, S., 2014. Oxidative and antioxidative mechanisms in oral cancer and precancer: a review. Oral oncology, 50(1), 10–18.

Alencar, D. B., Melo, A. A., Silva, G. C., Lima, R. L., Pires-Cavalcante, K., Carneiro, R. F., Rabelo, A. S., Sousa, O. V., Vieira, R. H., Viana, F. A., Sampaio, A. H., and Saker-Sampaio, S., 2015. Antioxidant, hemolytic, antimicrobial, and cytotoxic activities of the tropical Atlantic marine zoanthid Palythoa caribaeorum. Anais da Academia Brasileira de Ciências, 87, 1113–1123.

Wada, N., Sakamoto, T., and Matsugo, S., 2015. Mycosporine-like amino acids and their derivatives as natural antioxidants. Antioxidants, 4(3), 603–646.

Dunlap, W. C., and Yamamoto, Y., 1995. Small-molecule antioxidants in marine organisms: antioxidant activity of mycosporine-glycine. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 112(1), 105–114.

Han, C., Qi, J., Shi, X., Sakagami, Y., Shibata, T., Uchida, K., and Ojika, M., 2006. Prostaglandins from a zoanthid: Paclitaxel-like neurite-degenerating and microtubule-stabilizating activities. Bioscience, Biotechnology, and Biochemistry, 70(3), 706–711.

Yang, S. Y., Bourgeois, C., Ashworth, C. D., and Reimer, J. D., 2013. Palythoa zoanthid’barrens’ in Okinawa: examination of possible environmental causes. Zoological Studies, 52, 1–11.

Almeida, J. G. L., Maia, A. I. V., Wilke, D. V., Silveira, E. R., Braz-Filho, R., La Clair, J. J., Costa-Lotufo, L. V., and Pessoa, O. D. L., 2012. Palyosulfonoceramides A and B: unique sulfonylated ceramides from the Brazilian zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis. Marine Drugs, 10(12), 2846–2860.

Moore, R. E., and Scheuer, P. J., 1971. Palytoxin: a new marine toxin from a coelenterate. Science, 172(3982), 495–498.

Uemura, D., Hirata, Y., Iwashita, T., and Naoki, H., 1985. Studies on palytoxins. Tetrahedron, 41(6), 1007–1017.

Chen, S. R., Wang, S. W., Su, C. J., Hu, H. C., Yang, Y. L., Hsieh, C. T., Peng, C. C., Chang, F. R., and Cheng, Y. B., 2018. Anti-lymphangiogenesis components from Zoanthid Palythoa tuberculosa. Marine Drugs, 16(2), 47.

Lee, J. C., Chang, F. R., Chen, S. R., Wu, Y. H., Hu, H. C., Wu, Y. C., Backlund, A., and Cheng, Y. B., 2016. Anti-dengue virus constituents from Formosan Zoanthid Palythoa mutuki. Marine drugs, 14(8), 151.

Chen, S. R., Wang, S. W., Chang, F. R., and Cheng, Y. B., 2019. Anti-lymphangiogenic alkaloids from the zoanthid Zoanthus vietnamensis collected in Taiwan. Journal of Natural Products, 82(10), 2790–2799.

Chen, S. R., Wang, S. W., Sheu, J. H., Chang, T. H., and Cheng, Y. B., 2020. Zoanthamine Alkaloid Derivatives from the Zoantharian Zoanthus vietnamensis with Antimetastatic Activity. The Journal of Organic Chemistry, 85(19), 12553–12560.

Chen, S. R., Wang, S. W., Lin, Y. C., Yu, C. L., Yen, J. Y., Chen, Y. F., and Cheng, Y. B., 2021. Additional alkaloids from Zoanthus vietnamensis with neuro-protective and anti-angiogenic effects. Bioorganic Chemistry, 109, 104700.

Ramos, V., and Vasconcelos, V., 2010. Palytoxin and analogs: biological and ecological effects. Marine Drugs, 8(7), 2021–2037.

Domínguez-Pérez, D., Diaz-Garcia, C. M., García-Delgado, N., Sierra-Gómez, Y., Castañeda, O., and Antunes, A., 2013. Insights into the toxicological properties of a low molecular weight fraction from Zoanthus sociatus (Cnidaria). Marine drugs, 11(8), 2873–2881.

Pax, F., 1957. Zoantharien aus Viet-Nam. Mem Mus Natl Hist Nat (Paris), 16, 1–40.

Reimer, J. D., Wee, H. B., Put, A., and Hoeksema, B., 2015. Zoantharia (Cnidaria: Anthozoa: Hexacorallia) of the South China Sea and Gulf of Thailand: a species list based on past reports and new photographic records. Raffles Bulletin of Zoology, 63, 334–356.

Duan, X. J., Zhang, W. W., Li, X. M., and Wang, B. G., 2006. Evaluation of antioxidant property of extract and fractions obtained from a red alga, Polysiphonia urceolata. Food chemistry, 95(1), 37–43.

Ganesan, P., Kumar, C. S., and Bhaskar, N., 2008. Antioxidant properties of methanol extract and its solvent fractions obtained from selected Indian red seaweeds. Bioresource Technology, 99(8), 2717–2723.

Kumar, K. S., Ganesan, K., and Rao, P. S., 2008. Antioxidant potential of solvent extracts of Kappaphycus alvarezii (Doty) Doty–An edible seaweed. Food chemistry, 107(1), 289–295.

Hong, D. D., Vy, P. B., Thu, N. T. H., Khoi, T. X., Ha, N. C., and Tam, L. T., 2018. Evaluation of bioactivities and formulation of face mask from Sargassum sp. extract. Academia Journal of Biology (Tap Chi Sinh Hoc), 40(3), 106–112.

Thu, N. T. H., Vy, P. B., Khoi, T. V., Ha, N. C., Tam, L. T., Duc, T. M., and Hong, D. D., 2018. Evaluation of bioactivities and formulation face mask from brown seaweed (Padina sp.) extract. Proceeding of National Biotechnology Conference 2018, 212–217. (in Vietnamese)

Putra, M. Y., Murniasih, T., Swasono, R. T., Wibowo, J. T., Saputri, A. N. C., Widhiana, M. R., and Arlyza, I. S., 2016. Secondary metabolites and their biological activities in Indonesian soft coral of the genus Lobophytum. Asian Pacific Journal of Tropical Biomedicine, 6(11), 909–913.