Metabolites from the soft coral -associated bacterium \(\textit{Micrococcus}\) sp. strain a-2-28

Pham Thi Mien, Jutta Wiese, Dao Viet Ha
Author affiliations


  • Pham Thi Mien Institute of Oceanography, VAST, Vietnam
  • Jutta Wiese GEOMAR, Helmholtz Centre for Ocean Research Kiel- Düsternbrooker Weg 20, D-24105 Kiel, Germany
  • Dao Viet Ha Institute of Oceanography, VAST, Vietnam



Micrococcus sp., coral-associated, metabolites, compound purification, bioassays.


The marine actinomyces Micrococcus was the most common bacterium among the isolates corals, sponges, and alga isolates. Only a few investigations of natural compounds from Micrococcus sp. were reported previously. This study implicated the soft coral-associated Micrococcus sp. strain A-2-28 (following relative Micrococcus flavus LW4T) for large-scale cultivation, chemical analyses, and biological activities. Whereas crude extract of the strain A-2-28 inhibited only Staphylococcus epidermidis, metabolites profiles and pure compounds from strain A-2-28 showed that this strain produced phytohormone (IAA), metabolized some new compounds which were almost inactive for biological tests. This work suggested that it is possible to plan a new strategy for improving coral health and resilience though their associated microbial.


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How to Cite

Pham , T. M., Wiese, J., & Dao Viet Ha, D. V. H. (2023). Metabolites from the soft coral -associated bacterium \(\textit{Micrococcus}\) sp. strain a-2-28. Vietnam Journal of Marine Science and Technology, 23(2), 181–188.




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