Metabolites from the soft coral -associated bacterium \(\textit{Micrococcus}\) sp. strain a-2-28

Thi Mien Pham; Jutta Wiese; Dao Viet Ha Dao Viet Ha

doi:10.15625/1859-3097/18414

Author affiliations

Authors

Pham Thi Mien Institute of Oceanography, VAST, Vietnam
Jutta Wiese GEOMAR, Helmholtz Centre for Ocean Research Kiel- Düsternbrooker Weg 20, D-24105 Kiel, Germany
Dao Viet Ha Institute of Oceanography, VAST, Vietnam

DOI:

https://doi.org/10.15625/1859-3097/18414

Keywords:

Micrococcus sp., coral-associated, metabolites, compound purification, bioassays.

Abstract

The marine actinomyces Micrococcus was the most common bacterium among the isolates corals, sponges, and alga isolates. Only a few investigations of natural compounds from Micrococcus sp. were reported previously. This study implicated the soft coral-associated Micrococcus sp. strain A-2-28 (following relative Micrococcus flavus LW^4T) for large-scale cultivation, chemical analyses, and biological activities. Whereas crude extract of the strain A-2-28 inhibited only Staphylococcus epidermidis, metabolites profiles and pure compounds from strain A-2-28 showed that this strain produced phytohormone (IAA), metabolized some new compounds which were almost inactive for biological tests. This work suggested that it is possible to plan a new strategy for improving coral health and resilience though their associated microbial.

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