Screening of algae collected from Nha Trang bay, Vietnam, for potential cosmeceutical bioproducts

Kim Chi Hoang; Thi Hong Ha Tran; Ngoc Hung Truong; Thi Nhu Hang Tran; Thi Hong Tham Tran; Mai Huong Le; Huu Cuong Le

doi:10.15625/1859-3097/18020

Author affiliations

Authors

Hoang Kim Chi Institute of Natural Products Chemistry, VAST, Vietnam
Tran Thi Hong Ha Institute of Natural Products Chemistry, VAST, Vietnam
Truong Ngoc Hung Institute of Natural Products Chemistry, VAST, Vietnam
Tran Thi Nhu Hang Institute of Natural Products Chemistry, VAST, Vietnam
Tran Thi Hong Tham VNU University of Science, Hanoi, Vietnam; Vietnam-Poland High School, Hanoi, Vietnam
Le Mai Huong Institute of Natural Products Chemistry, VAST, Vietnam
Le Huu Cuong Institute of Natural Products Chemistry, VAST, Vietnam

DOI:

https://doi.org/10.15625/1859-3097/18020

Keywords:

Marine algae, antioxidant, cosmeceutical, cytotoxicity, tyrosinase inhibition, Ulva lactuca.

Abstract

As marine seaweeds are a great source of natural products, investigating biological properties for appropriate management and exploitation is a priority. For our study, we collected and extracted indigenous algal samples from marine areas of Nha Trang bay belonging to nine species of Chlorophyta, Rhodophyta, and Ochophyta to investigate their cosmeceutical activities. Results revealed tyrosinase inhibitory activity of methanolic extracts of Halimeda sp. and Ulva lactuca with 57.17 ± 1.70% and 54.32 ± 0.52% of inhibition, respectively. Additionally, methanolic extracts of U. lactuca, Sargassum mcclurei, and S. aquifolium were found to perform moderate scavenging capacity against DPPH free radicals. By the colorimetric method, the algae extracts were determined to exhibit no potent cytotoxic effect on both fibroblast cell line NIH-3T3 and keratinocyte cell line HaCaT at a test concentration of 20 µg/mL and thus considered promising for further safety evaluation. The investigation provides information on biological activities of our marine algae and highlights candidates with application significance.

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