EVALUATION OF BIOACTIVITIES AND FORMULATION FACE MASK FROM Sargassum sp. EXTRACT

Phan Bao Vy, Ngo Thi Hoai Thu, Tran Xuan Khoi, Nguyen Cam Ha, Luu Thi Tam, Dang Diem Hong

Abstract


Brown seaweeds, particularly Sargassum genus, contain large amounts of polysaccharides, such as alginate and fucoidan which are widely applied to related health care approaches. Obviously, this genus is a potential alternative resource for cosmetic industry with its extract gained a great deal of biochemical composition and bioactivity. This study showed that the protein, lipid, total carbohydrate, chlorophyll and carotenoid content of Sargassum sp. which collected in Khanh Hoa, Vietnam were 10.45 ± 1.15 %, 1.90 ± 0.12 %, 50.55 ± 1.05 %, 0.25 ± 0.03 mg/g and 0.104 ± 0.001 mg/g of dry weight (DW), respectively. The hot water extract of Sargassum sp. showed high antioxidant activity (85.82 ± 1.89 % at 50 mg/mL), antibacterial activity with the range of minimal inhibitory concentrations (MIC) from 25 - 100 mg/mL and tyrosinase inhibitory activity with 40.06 ± 1.15 %. The formula of face mask from 10% of Sargassum sp. extract gained antioxidant and tyrosinase inhibitory activity with 61.67 ± 0.06 % and 29.064 ± 0.06 %, respectively. This product was also evaluated for the physical properties included organoleptic (brown color with specific odor), pH, homogeneity, spread ability and irritation test. The bacterial criteria, heavy metal levels of face mask were also recognized to evaluate for safety of human health following Ministry of Health standard.

Keywords


antibacterial, antioxidant, biochemical composition, face mask, Sargassum sp. extract, tyrosinase inhibitory activity



DOI: https://doi.org/10.15625/2615-9023/v40n3.12686

Published by Vietnam Academy of Science and Technology