Chemical composition and antimicrobial activity of essential oils from \(\textit{Angelica sinensis}\) (Oliv.) diels cultivated in Hung Yen province of Vietnam

Chu Thi Thu Ha; Nguyen Thi Huong; Nguyen Phuong Hanh; Nguyen Quang Hung; Nguyen Khang  Sinh; Dinh Thi Thu  Thuy; Tran Thi  Tuyen; Nguyen Thi Hong  Ngoc; Nguyen Kieu Bang  Tam; Nguyen Thuy Hang

doi:10.15625/2615-9023/15634

Author affiliations

Authors

Chu Thi Thu Ha Institute of Ecology and Biological Resources, VAST, Vietnam https://orcid.org/0000-0002-3479-9469
Nguyen Thi Huong Institute of Ecology and Biological Resources, VAST, Vietnam
Nguyen Phuong Hanh Institute of Ecology and Biological Resources, VAST, Vietnam
Nguyen Quang Hung Institute of Ecology and Biological Resources, VAST, Vietnam
Nguyen Khang Sinh Institute of Ecology and Biological Resources, VAST, Vietnam
Dinh Thi Thu Thuy Institute of Natural Product Chemistry, VAST, Vietnam
Tran Thi Tuyen Institute of Natural Product Chemistry, VAST, Vietnam
Nguyen Thi Hong Ngoc VNU, University of Science, Ha Noi, Vietnam
Nguyen Kieu Bang Tam VNU, University of Science, Ha Noi, Vietnam
Nguyen Thuy Hang Vietnam National University of Agriculture, Ha Noi, Vietnam

DOI:

https://doi.org/10.15625/2615-9023/15634

Keywords:

Angelica sinensis, essential oil composition, antimicrobial activity

Abstract

Essential oils from roots, flowers, fruits, and leaves plus stems of Angelica sinensis cultivated in Vietnam were obtained by hydrodistillation and were analyzed using GC/MS-FID. In total, 36, 30, 33, and 27 compounds were found accounting for 98.7%, 98.8%, 99.2%, and 100% of the oils compositions, respectively. (Z)-Ligustilide (49.4%, 29.6%, 25.8%, 28.9%) and γ-terpinene (20.6%, 38.5%, 35.5%, 44.2%) were the main components of the respective essential oils. Especially, dictyopterene C (10.8%) was found to be one of the main components of fruit oil. Among the A. sinensis essential oil samples tested, the fruit oil revealed the strongest antimicrobial activity against bacteria Escherichia coli and yeast Candida albicans with median inhibitory concentration values of 0.97 and 0.15 mg/mL, respectively.

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