Sterols from Vietnamese marine sponge Tethya aurantium

Nguyen Thi Cuc, Dan Thi Thuy Hang, Bui Huu Tai, Nguyen Xuan Nhiem, Hoang Le Anh Tuan, Pham Hai Yen, Vu Van Doan, Chau Van Minh, Phan Van Kiem
Author affiliations

Authors

  • Nguyen Thi Cuc
  • Dan Thi Thuy Hang
  • Bui Huu Tai
  • Nguyen Xuan Nhiem
  • Hoang Le Anh Tuan
  • Pham Hai Yen
  • Vu Van Doan
  • Chau Van Minh
  • Phan Van Kiem

DOI:

https://doi.org/10.15625/7613

Keywords:

Steroid, Tethya aurantium, Vietnamese sponge.

Abstract

Chemical investigation on Vietnamese marine sponge Tethya aurantium resulted in the isolation of five sterols, including 5R,6R-epoxy-24R*-ethylcholesta-8-en-3β,7α-diol (1), 24-methylenecholesta-5-en-3β-ol (2), 24-norcholesta-5,22E-dien-3β-ol (3), 5α,8α-epidioxy-24R*-ethylcholesta-6-en-3β-ol (4), and 5α,8α-epidioxy-24S-methylcholesta-6,22E-dien-3β-ol (5). Their chemical structures were successfully determined using NMR and ESI-MS analysis as well as in comparison with the reported literatures. Stereochemistry of C-24 in the side chain of isolated sterols was also discussed. This is the first study on chemical constituents from the sponge T. aurantium.

Keywords. Steroid, Tethya aurantium, Vietnamese sponge.

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Published

01-12-2015

How to Cite

Cuc, N. T., Thuy Hang, D. T., Tai, B. H., Nhiem, N. X., Anh Tuan, H. L., Yen, P. H., Doan, V. V., Minh, C. V., & Kiem, P. V. (2015). Sterols from Vietnamese marine sponge Tethya aurantium. Vietnam Journal of Chemistry, 53(5), 585. https://doi.org/10.15625/7613

Issue

Vol. 53 No. 5 (2015)

Section

Articles