Cembranoid constituents from lobophytum crassum
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DOI:
https://doi.org/10.15625/6218Keywords:
Five cembranoids, 2, 16, 7S, 8S-diepoxy-1, 3, 11, 15-cembratetraene (1), 8S-epoxy-1, 11-cembratriene-16-oic acid methyl ester (2), (1R, 4R, 2E, 7E, 11E)-cembra-2, 7, 11-triene-4-ol (3), (2S, 8S)-sarcophine (4), and (2S, 8S)-sarcophytoxide (5), were isolated fAbstract
Five cembranoids, 2,16:7S,8S-diepoxy-1,3,11,15-cembratetraene (1), 7S,8S-epoxy-1,3,11-cembratriene-16-oic acid methyl ester (2), (1R,4R,2E,7E,11E)-cembra-2,7,11-triene-4-ol (3), (2S,7S,8S)-sarcophine (4), and (2S,7S,8S)-sarcophytoxide (5), were isolated from the methanol extract of the soft coral Lobophytum crassum by using various chromatographic methods. Their structures were elucidated by 1D and 2D-NMR experiments and comparison of their NMR data with reported values. Compounds 1 and 3 were isolated from L. crassum for the first time.