Tổng hợp 21-acetat pregn-4,9(11)-dien-17α,21-diol-3,20-dion
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DOI:
https://doi.org/10.15625/0866-7144.2014-0009Keywords:
21-acetate pregna-4, 9(11)-diene-17α, 21-diol-3, 20-dione, 9α-hydroxy androstenedioneAbstract
In this paper, we present the synthesis of the 21-acetate pregna-4,9(11)-diene-17α,21-diol-3,20-dione from 9α- hydroxy androstenedione, an important intermediate for synthesis of corticoids such as hydrocortisone and prednisolone. The structure of the product and its intermediates was examined by physical methods such as: IR, MS, 1H and 13C NMR.
Keywords: 21-acetate pregna-4,9(11)-diene-17α,21-diol-3,20-dione, 9α-hydroxy androstenedione.
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Published
17-09-2014
How to Cite
Huy, L. Đức, Diệp, N. T., Thảo, P. T., & Hùng, L. Đức. (2014). Tổng hợp 21-acetat pregn-4,9(11)-dien-17α,21-diol-3,20-dion. Vietnam Journal of Chemistry, 52(4), 443. https://doi.org/10.15625/0866-7144.2014-0009
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