Investigating the phytochemical production and antioxidant activity in four plant species belonging to the <i>asteraceae</i> family

Thi Van Anh Le; Ngoc Trung Anh Tran; Thi Hien Diu Dinh; Phuong Anh Duong; Tran Bao Chau Ha; Nga Thi Phuong Mai

doi:10.15625/vjbt-21592

Author affiliations

Authors

Thi Van Anh Le \(^1\) University of Science and Technology of Hanoi- Vietnam academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, 10000, Vietnam. https://orcid.org/0000-0002-4072-4770
Ngoc Trung Anh Tran \(^1\) University of Science and Technology of Hanoi- Vietnam academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, 10000, Vietnam. https://orcid.org/0009-0007-4617-7943
Thi Hien Diu Dinh \(^1\) University of Science and Technology of Hanoi- Vietnam academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, 10000, Vietnam. https://orcid.org/0009-0004-0688-8036
Phuong Anh Duong \(^1\) University of Science and Technology of Hanoi- Vietnam academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, 10000, Vietnam. https://orcid.org/0009-0004-1635-2171
Tran Bao Chau Ha \(^1\) University of Science and Technology of Hanoi- Vietnam academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, 10000, Vietnam.
Nga Thi Phuong Mai \(^1\) University of Science and Technology of Hanoi- Vietnam academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Ha Noi, 10000, Vietnam. https://orcid.org/0000-0002-8492-4141

DOI:

https://doi.org/10.15625/vjbt-21592

Keywords:

Antioxidant, Asteraceae, flavonoid, free radical scavenging activity, phenolic, secondary metabolites

Abstract

Vietnam has a rich and profound traditional medicine system that is widely used today. Medicinal plants are used to treat colds, coughs, bone and joint diseases, digestion, respiratory diseases, etc. In this study, leaves of Artemisia vulgaris, Taraxacum officinale, Blumea balsamifera, and flowers of Xerochrysum bracteatum from the Asteraceae family were selected to determine the antioxidant capacity and relationship with the active ingredients in the plants. The methanolic extracts were screened for chemical compositions via the total phenolic content (TPC) assay, the total flavonoid content (TFC) assay, and DPPH radical scavenging activity. The highest radical scavenging activity was observed in the flowers of X. bracteatum (IC₅₀ = 0.061 mg/mL), followed by the leaves of Taraxacum (IC₅₀ = 0.313 mg/mL), A. vulgaris (IC₅₀ = 1.367 mg/mL), and B. balsamifera (IC₅₀ = 1.4502 mg/mL). The TPC of the studied plants ranged from 19.98 ± 1.355 to 195.78 ± 42.518 mgGAE/g extract, while the TFC ranged from 60.31 ± 1.725 to 339.14 ± 26.299 mgQE/g extract. The highest TPC and TFC were recorded in the methanol extract of X. bracteatum. The strongly negative correlation between the TPC and TFC and the IC₅₀ values (R²= -0.78, R² = -0.76) suggests that TFC and TPC could strongly contribute to the antioxidant activity of these plants. These results not only highlight the relevance of these plants in traditional medicine but also scientifically validate their use, particularly in the context of their antioxidant properties. The study underscores the close relationship between the traditional use of these plants and their scientifically observed effects, reinforcing the value of folk remedies.

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