Terpenoids from Dacrycarpus imbricatus.
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DOI:
https://doi.org/10.15625/2525-2321.2017-00535Keywords:
Dacrycarpus imbricatus, spathulenol, pimaric acid, communic acidAbstract
The phytochemical investigation of the hexane extract from the twigs and leaves of Dacrycarpus imbricatus (Blume) de Laub led to the isolation of a rare sesquiterpene, spathulenol (1) along with three diterpenes named pimaric acid (2), trans-communic acid (3) and cis-communic acid (4). Their structures were determined by combination of spectral analysis and comparison with reported data. This is the first report on isolation of compound 1 from the Podocarpaceae family.
Keywords. Dacrycarpus imbricatus, spathulenol, pimaric acid, communic acid.
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References
Ning Li, Qi Deng, Lu Huang, Yingjuan Su, Ting Wang. Isolation and characterization of ten polymorphic microsatellite loci for a vulnerable species Dacrycarpus imbricatus (Podocarpaceae) in China, Biochemical Systematics and Ecology, 54, 83-87 (2014).
Trinh Thi Thuy, Nguyen Thanh Tam, Nguyen Thi Hoang Anh, Dang Viet Hau, Dinh Thi Phong, Le Quoc Thang, Sabrina Adorisio, Tran Van Sung, Domenico V Delfino. 20-Hydroxyecdysone from Dacrycarpus imbricatus bark inhibits the proliferation of acute myeloid leukemia cells, Asian Pacific Journal of Tropical Medicine, 10(2), 157-159 (2017).
Ammanamanchi S. R. Anjaneyulu, Kadali S. Sagar, Mukku J. R. V. Venugopal. Terpenoid and steroid constituents of the Indian Ocean soft coral Sinularia maxima, Tetrahedron, 51(40), 10997-11010 (1995).
Consolacion Y. Ragasa, Jerome Ganzon, Joy Hofilena, Benjie Tamboong, John A. Rideout. A new furanoid diterpene from Caesalpinia pulcherrima, Chem. Pharm. Bull., 51(10), 1208-1210 (2003).
Dictionary of Natural Products on DVD, version 5.1 (2012).
Junichi Kitajima, Tetsuya Komori, Toshio Kawasaki. Studies on the constituents of the crude drug Fritillaria bulbus: III. On the diterpenoid constituents of fresh bulbs of Fritillaria thunbergii Miq., Chem. Pharm. Bull., 30(11), 3912-3921 (1982).
Mineo Shimizu, Hideki Tsuji, Hisashi Shogawa, Hideki Fukumura, Seiichi Tanaami, Toshimitsu Hayashi, Munehisa Arisawa and Naokata Morit. Anti-inflammatory constituents of topically applied crude drugs. II. Constituents and anti-inflammatory effect of Cryptomeria japonica D. DON, Chem. Pharm. Bull., 36(10), 3967-3973 (1988).
Jim-Min Fang, Kuo-Chio Hsu and Yu-Shia Cheng. Terpenoids from Calocedrus formosana, Phytochemistry, 28(4), 1173-1175 (1989).
Likhitwitayawuid K., Angerhofer C. K., Cordell G. A., Pezzuto J. M., Ruangrungsi N. Cytotoxic and antimalarial bisbenzylisoquinolone alkaloids from Stephania erecta, Journal of Natural Products, 56(1), 30-38 (1993).
Skehan P., Storeng R., Scudiero D., Monks A., Mahon MJ., Vistica D., Warren JT., Bokesch H., Kenney S,, Boyd MR. New colorimetric cytotoxicity assay for anticancer-drug screening, Journal of the National Cancer Institute, 82, 1107-1112 (1990).