Nghiên cứu một số hợp chất thứ cấp từ chủng xạ khuẩn Streptomyces sp. (G065).
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DOI:
https://doi.org/10.15625/0866-7144.2017-00410Keywords:
Streptomyces sp., marine microorganism, Cyclo-(Pro-Ala), Cyclo-(Pro-Val), Cyclo-(Pro-Leu), Cyclo- (Pro-Tyr), Cyclo-(Pro-Trp).Abstract
Eight secondary metabolites, Cyclo-(Pro-Ala) (1), Cyclo-(Pro-Val) (2), Cyclo-(Pro-Leu) (3), Cyclo-(Pro-Tyr) (4), Cyclo-(Pro-Trp) (5), n-butyl-isobutyl phthalate (6), phenylacetic acid (7) and uracil (8) were isolated and identified from Streptomyces sp. (G065). Their structures were determined by spectroscopic analysis including MS and 2D NMR, as well as by comparison with reported data in literature.
Keywords. Streptomyces sp., marine microorganism, Cyclo-(Pro-Ala), Cyclo-(Pro-Val), Cyclo-(Pro-Leu), Cyclo- (Pro-Tyr), Cyclo-(Pro-Trp).
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References
Châu Văn Minh, Phan Văn Kiệm, Nguyễn Văn Hùng, Nguyễn Hoài Nam, Phạm Văn Cường. Dược liệu biển Việt Nam thực trạng và cơ hội phát triển, Nxb. Khoa học tự nhiên và Công nghệ, Hà Nội, tr. 3 (2012).
Lê Gia Hy. Nghiên cứu xạ khuẩn thuộc chi Streptomyces sinh chất kháng sinh cống nấm gây bệnh đạo ôn và thối cổ rễ phân lập ở Việt Nam, Luận án Tiến sĩ Sinh học, Hà Nội (1994).
Vu Thi Quyen, Le Thi Hong Minh, Vu Van Nam, Le Cong Vinh, Nguyen Mai Anh, Pham Viet Cuong, Nguyen Thi Kim Cuc, Doan Thi Mai Huong, Brian T. Murphy, Pham Van Cuong, Chau Van Minh. Biological characteristics of streptomyce sp. Isolated from marine sediments of Van Phong bay and antimicrobial activity of crude extracts of some isolated, Vietnam Journal of Chemistry, 53(2e), 188-193 (2015).
Z. F. Fang, S. S. Yu, W. Q. Zhou, X. G. Chen, S. G. Ma, Y. Li, J. Qu. A new isocoumarin from metabolites of the endophytic fungus Alternaria tenuissima Wiltshire, Chinese Chemical Letters, 23, 317-320 (2012).
X. J. Li, Q. Zhang, A. L. Zhang, and J. M. Gao. Metabolites from Aspergillus fumigates, an Endophytic Fungus Associated with Melia azedarach, and Their Antifungal Antifeedant and Toxic Activities, Journal of Agricultural and Food Chemistry, 60, 3424-3431 (2012).
C-Y. Wang, L. Han, K. Kang, C-L. Shao, Y-X Wei, C-J Zheng and H-S. Guan. Secondary metabolites from green algae Ulva pertusa, Chem. Nat. Compd., 46(5), 828-830 (2010).
S. Smaoui, F. Mathieu, L. Elleuch, Y. Coppe, G. Merlina, I. Karray-Rebai, L. Melloul. Taxonomy purification and chemical characterization of four bioactive compounds from new Streptomyces sp. TN256 strain, World Journal of Microbiology and
Biotechnology, 28, 793-804 (2011).
Y.-M. Ying, W.-G. Shan, W-H. Liu and Zha-J. Zhan. Alkaloids and nucleoside derivatives from a fungal endophyte of Huperzia serrata, Chem. Nat. Compd., 49(1), 184-186 (2003).
M. Liu, W. Zhang, L. Qiu, X. Lin. Synthesis of butyl-isobutyl-phthalate and interraction with α-glucosi-
dase in vitro, J. Biochem., 149(1), 27-33 (2011).
B. K. Hwang, S. W. Lim, B. S. Kim, J. Y. Lee and S. S. Moon. Isolation and In Vivo and In Vitro Antifungal Activity of Phenylacetic Acid and Sodium Phenylacetate from Streptomyces humidus, Applied and Environmental Microbiology, 67(8), 3739-3745 (2001).