Analysis of the complete mitochondrial genome of Vietnamese <i> Pygathrix nigripes</i>

Thi Thuy Tram Nguyen; Thanh Long Le; Nguyen Quynh Chi Ho; Luu Chinh Nhan Phan; Thanh Tung Ha; Thi Tung Loan Dang; Thi Phuong Mai Nguyen

doi:10.15625/vjbt-21785

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Authors

Thi Thuy Tram Nguyen \(^1\) Biotechnology Department, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
\(^2\) University of Physical Education and Sport, 629 Nguyen Trai street, Ward 11, District 5, Ho Chi Minh city, Vietnam https://orcid.org/0009-0007-3733-744X
Thanh Long Le \(^1\)Biotechnology Department, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
\(^3\)Animal Biotechnology Department, Institute of Tropical Biology, Vietnam Academy of Science and Technology, 9/621 Hanoi highway, Linh Trung ward, Thu Duc district, Ho Chi Minh city, Vietnam https://orcid.org/0000-0003-4732-3643
Nguyen Quynh Chi Ho \(^1\)Biotechnology Department, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
\(^3\)Animal Biotechnology Department, Institute of Tropical Biology, Vietnam Academy of Science and Technology, 9/621 Hanoi highway, Linh Trung ward, Thu Duc district, Ho Chi Minh city, Vietnam
Luu Chinh Nhan Phan \(^3\) Animal Biotechnology Department, Institute of Tropical Biology, Vietnam Academy of Science and Technology, 9/621 Hanoi highway, Linh Trung ward, Thu Duc district, Ho Chi Minh city, Vietnam
Thanh Tung Ha \(^4\) Taynguyen Institute for Scientific Research, Academy of Science and Technology, 116 Xo Viet Nghe Tinh street, Ward 7, Da Lat city, Lam Dong province, Vietnam
Thi Tung Loan Dang \(^5\) University of Science, Vietnam National University, 227 Nguyen Van Cu street, Ward 4, District 5, Ho Chi Minh city, Vietnam
Thi Phuong Mai Nguyen \(^4\)Taynguyen Institute for Scientific Research, Academy of Science and Technology, 116 Xo Viet Nghe Tinh street, Ward 7, Da Lat city, Lam Dong province, Vietnam

DOI:

https://doi.org/10.15625/vjbt-21785

Keywords:

AT skew, endangered, genetic diversity, mitochondrial, Vietnamese Pygathrix nigripes

Abstract

The black-shanked douc langur Pygathrix nigripes is a critically endangered primate species endemic to Vietnam, facing severe threats from habitat destruction, poaching, and climate change. This study presents the complete mitochondrial genome of Pygathrix nigripes, comprising 16,535 bp, which includes 37 genes: 13 protein-coding genes, 22 transfer RNAs, and 2 ribosomal RNAs. Mitochondrial genomes are crucial for cellular energy metabolism, and understanding their genetic structure is vital for effective conservation strategies. Our analysis reveals significant genetic diversity and an A-T rich nucleotide composition, characteristic of primate mitogenomes, indicating adaptive evolutionary strategies. The study also highlights the importance of mitochondrial protein-coding genes in energy production and metabolic efficiency, which are critical for the species' survival. We observed variations in nucleotide composition and codon usage bias that reflect historical population dynamics and evolutionary pressures. Comparative genomic analyses with other Pygathrix species suggest shared evolutionary pathways, emphasizing the need for targeted conservation efforts. The findings underscore the necessity of genetic monitoring in conservation planning, particularly as Pygathrix nigripe faces ongoing environmental challenges. This research aims to enhance the global mapping of the Pygathrix nigripes mitogenome, offering valuable insights that can support the development of effective conservation strategies. These strategies are essential for ensuring the survival of this unique and critically endangered primate species.

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