TY - JOUR AU - Ha, Chu Duc AU - Dung, Le Tien PY - 2016/01/27 Y2 - 2024/03/29 TI - The role of cis- regulatory elements in abiotic- stress responses in plants JF - Academia Journal of Biology JA - AJB VL - 37 IS - 3 SE - Articles DO - 10.15625/0866-7160/v37n3.7454 UR - https://vjs.ac.vn/index.php/vjbio/article/view/7454 SP - 370-383 AB - <p>Recent advances in plant biology research, particularly in genetic engineering, had provided new tools to mitigate food security caused by climate changes and rapid population growth. <em>Cis-</em>regulatory elements, usually located in the upstream of the promoter region, are the binding sites for transcription factors, and thus, control the expression of the gene. There are several important <em>cis</em>-regulatory elements, such as ABRE-involved in the abscisic acid responsiveness; MYBRS and MYCRS - drought responsive elements; DRE and LTRE - temperature responsive elements. Previous studies have shown the importance of <em>cis</em>-regulatory elements in stress-adaptation in plants. In this review, we summarized and discussed the roles of <em>cis­</em>- regulatory elements in the adaptation of plants to abiotic stress and its application potential in development of stress-tolerant plants. Throughout the review, we showed that <em>cis</em>-elements could be parts of potential approaches for genetic engineering toward improved crop varieties. Furthermore, we also discussed the possibility to apply genome editing as a tool, such as CRISPR/Cas9 system, to redesign the <em>cis</em>-elements in the promoters of stress-responsive genes to generate <em>“</em><em>edited crops</em><em>” </em>with enhanced stress tolerance through modulating gene expression. <em></em></p> ER -