TY - JOUR AU - Hung, Do Manh AU - Ha, Nguyen Hai AU - Khoi, Pham Nhat AU - Nhung, Vu Phuong AU - Phong, Nguyen Van AU - Duong, Nguyen Thuy AU - Hai, Nong Van AU - Ton, Nguyen Dang PY - 2016/04/25 Y2 - 2024/03/29 TI - Genetic variation of mitochondrial sequence-hv2 in Vietnamese populations JF - Academia Journal of Biology JA - AJB VL - 38 IS - 2 SE - Articles DO - 10.15625/0866-7160/v38n2.7071 UR - https://vjs.ac.vn/index.php/vjbio/article/view/7071 SP - 243-249 AB - <p>HV1 and HV2, which located in control D-loop region of mitochondrial, are the hyper-variable parts of mitochondrial DNA (mtDNA). Therefore, these two sequences were often used for evolutional and forensic science. In order to determine the genetic variation of populations belong to Nam-A and Nam-Dao language systems, we sequenced and analyzed the mtDNA HV2 region of individuals from four ethic groups: Kinh, Muong, Ede and Jarai which represent for those language systems. Study subjects are peripheral blood of 169 individuals belonging to four populations: Kinh, Muong, Ede and Jarai. HV2 regions were sequenced by Sanger sequencing. As a result, the analyzed mitochondrial control region sequences could be assigned to 79 different haplogroups, with the dominant proportion of three haplogroups: R, B and F. Donors representing Kinh or Muong population revealed higher haplogroup composition variation in comparison with those affiliated with Jarai or Ede. In addition, it was indicated that the 4 populations shared the genetic analogy with other populations inhabited in Southeast Asia and South Asia.</p><p> </p> ER -