TY - JOUR AU - Quyen, Dong Van AU - Khang, Dinh Duy AU - Gyu, Yu Gyun PY - 2015/09/02 Y2 - 2024/03/29 TI - Molecular cloning and sequence of the pres domain of human hepatitis b surface antigen JF - Academia Journal of Biology JA - AJB VL - 25 IS - 4 SE - Articles DO - 10.15625/0866-7160/v25n4.6854 UR - https://vjs.ac.vn/index.php/vjbio/article/view/6854 SP - 32-36 AB - <p>By using nested PCR with specific primers, we have amplified and cloned the <em>pre</em>S domain, including 170 nucleotides of the S domain of the hepatitis B virus surface antigen (HBsAg) from human liver tumor biopsies. The sequence of this isolated <em>pre</em>S domain was compared with other <em>pre</em>S domains from the International Gene Bank Database. The identity ranges from 90 to 97%. These results suggested that the HBV strain isolated from Vietnamese patient was an adr subtype.</p> ER -