@article{Hoai Trinh_Duy Ngoc_Ly_Hung_Thuy Hang_Dieu Trang_Nhu Khanh_2016, title={Antibacterial activity of marine bacteria isolated from marine sponges at Phu Quoc island, Vietnam}, volume={38}, url={https://vjs.ac.vn/index.php/vjbio/article/view/7074}, DOI={10.15625/0866-7160/v38n1.7074}, abstractNote={<p>Screening antibacterial activity of fifty marine bacterial strains isolated from twenty-three species of marine sponges from Phu Quoc island. Among them, twenty-one strains (42%) have the ability to inhibit effectively at least two of the ten strains of the tested bacteria. Especially, the strain 045-203-4 showed strong antibacterial activity against six strains of pathogenic bacteria for humans and marine organisms, viz. <em>Pseudomonas aeruginosa, Escherichia coli, Vibrio harveyi, Klebsiella pneumoniae, Bacillus cereus </em>and<em> Streptococcus faecalis</em>. The strain 045-203-4 produced antibacterial with high activity in the medium contained yeast extract (0.8% w/v), glucose (0.5%), pH 7.0 for 30 hours. Analysis of the nucleotide sequence of 16S rRNA gene of strain 045-203-4 showed a strong similarity (99%) with the 16S rRNA gen of <em>Bacillus</em> <em>subtilis. </em>The present investigation reveals that the marine bacteria isolated from marine sponges from Phu Quoc island can be served as a potential source for the study and application of compounds with biological activity.</p>}, number={1}, journal={Academia Journal of Biology}, author={Hoai Trinh, Phan Thi and Duy Ngoc, Ngo Thi and Ly, Bui Minh and Hung, Le Dinh and Thuy Hang, Cao Thi and Dieu Trang, Vo Thi and Nhu Khanh, Huynh Hoang}, year={2016}, month={Mar.}, pages={109–114} }