@article{Tung_Nguyen_Xuan_Ha_Tien_2021, title={Elucidation of the biosynthetic pathway of B-group vitamins via genome mining of food-derived </i>Bacillus velezensis</i> VTX20}, volume={43}, url={https://vjs.ac.vn/index.php/vjbio/article/view/16624}, DOI={10.15625/2615-9023/16624}, abstractNote={&lt;p&gt;B-vitamins are micronutrients that play an important role in various cellular processes of organisms, which are only synthesized by plants, yeasts, and bacteria. Since animals and humans lack the ability to synthesize B-vitamins, supplements of vitamins from dietary and the B-vitamin producing bacteria are required. In this study, we, for the first time, shed some light on biosynthetic pathways involved in folate (vitamin B9), riboflavin (vitamin B2), and biotin (vitamin B7) production in &lt;em&gt;Bacillus velezensis&lt;/em&gt; VTX20. The genome-wide comparison revealed that &lt;em&gt;B. velezensis&lt;/em&gt; VTX20 shared high similarities with &lt;em&gt;B. tequilensis &lt;/em&gt;KCTC 13622, &lt;em&gt;B. subtilis &lt;/em&gt;168, &lt;em&gt;B. amyloliquefaciens&lt;/em&gt; DSM 7. Genomic analysis revealed the presence of a complete folate biosynthesis pathway in which some core components were not found in most &lt;em&gt;Bacillus&lt;/em&gt; species. Moreover, strain VTX20 also had the metabolic pathways for riboflavin and biotin that are important probiotic traits. These results highlighted that &lt;em&gt;B. velezensis&lt;/em&gt; VTX20 is a producer of B-vitamins, which can be applied further in the agricultural biotechnology industry.&lt;/p&gt;}, number={4}, journal={Academia Journal of Biology}, author={Tung, Quach Ngoc and Nguyen, Vu Thi Hanh and Xuan, Le Thi Thanh and Ha, Chu Hoang and Tien, Phi Quyet}, year={2021}, month={Dec.}, pages={153–159} }