Antifungal, antibacterial and cytotoxic activities of some Ardisia species from Vietnam

Abstract

Methanol extracts of nine species of the genus Ardisia from Vietnam were screened for antifungal, antibacterial and cytotoxic activities. The obtained results showed that the methanol extract of A. incarnata exhibited the strongest cytotoxic activity against all five tested cancer cell lines with IC₅₀ values ​​ranging from 5.26 to 8.46 mg/ml, and resisted A. niger with the MIC value 200 mg/ml. The methanol extracts of A. balansana, A. caudata, A. insularis, A. pseudocrispa, A. splendens have moderate cytotoxic and antimicrobial activities. The methanol extracts of A. maculosa, A. tsangii, A. primulifolia did not show cytotoxic and antimicrobial activities.