TY - JOUR AU - Tuan Anh, Hoang Le AU - Thi Dung, Duong AU - Tuan, Do Thanh AU - Hung, Trieu Quy AU - Hai Yen, Pham Thi AU - Quang, Tran Hong AU - Nhiem, Nguyen Xuan AU - Minh, Chau Van AU - Hai Yen, Duong Thi AU - Kiem, Phan Van PY - 2017/04/17 Y2 - 2024/03/29 TI - Hepatoprotective effects of phenolic glycosides from the methanol extract of Physalis angulata JF - Vietnam Journal of Science and Technology JA - Vietnam J. Sci. Technol. VL - 55 IS - 2 SE - Natural Products DO - 10.15625/0866-708X/55/2/8527 UR - https://vjs.ac.vn/index.php/jst/article/view/8527 SP - 161-167 AB - By various chromatographic separations, four phenolic glycosides, methyl salicylate 2-<em>O</em>-triglycoside (<strong>1</strong>), icariside E<sub>5</sub> (<strong>2</strong>), quercetin 3-<em>O</em>-rutinoside (<strong>3</strong>), and isorhamnetin 3-<em>O</em>-rutinoside (<strong>4</strong>) were isolated from the methanol extract of the whole plant of <em>Physalis angulata</em>. Their structures were determined by 1D-, 2D-NMR spectroscopic analyses and in comparison with the reported data. Compounds <strong>3</strong> exhibited significantly hepatoprotective activity with an EC<sub>50</sub> value of 17.08 µg/mL. This is the first report of <strong>1</strong>-<strong>4 </strong>from <em>Physalis angulata</em><em>.</em> ER -