SOME TERPENE COMPOUNDS ISOLATED FROM CALLICARPA MACROPHYLLA (L.) SPECIES IN VIETNAM
Keywords:Callicarpa macrophylla, sterol, triterpene and diterpene
Callicarpa macrophylla L. (Tu Chau la to) usually used in Vietnam traditional medicine for gastrointestinal bleeding, nosebleeds, in addition, it is also used for treating osteoarthritis pain. Phytochemical investigation of the n-hexan and ethyl acetate extract of Callicarpa macrophylla L. led to the isolation of β-sitosterol (1), β-sitosterol-3-O-β-D-glucopyranoside (2), stigmasta-7,22-dien-3β-ol (3), β-amyrin (4), ent-1α-acetoxy-7β,14α-dihydroxy-kaur-16-en-15-on (5) và ent-7β,16,17,18-tetrahydroxy-kaur-16-en-15-on (6). Their chemical structures were determined by spectroscopic methods including MS, 1D, 2D NMR and comparing with those reported in previous papers. Three compounds 4, 5, 6 were isolated for the first time from Callicarpa macrophylla plant.
Nguyen Tien Ban et al. - Checklist of Plant Species of Vietnam. Agriculture Publishing House, Hanoi, III (2003) 286.
Vo Van Chi, - Vietnamese Medical Plants Dictionary. Medicine Publishing House, (2012), 1123-1124.
Rajesh Kumar Soni,Vihangesh Dixit, Raghuveer Irchhaiya and Shashi Alok, - Callicarpa macrophylla: A review update on ít botany, ethnobotany, phytochemistry and pharmacology. Rajesh KS., IJP, 1(2) (2014) 87-94.
Zhen-Hui Wang, Jian Huang, Chao Niu, Jin-Hui Wang, Bin Wu, - Isopimarane-type diterpenoids from Callicarpa macrophylla vahl, Phytochemistry Letters 22 (2017) 224–228.
Jing Xu,Yihang Sun, Meicheng Wang, Quanhui Ren, Shen Li, Hao Wang, Xiaocong Sun, Da-Qing Jin, Hongwei Sun, Yasushi Ohizumi, and Yuanqiang Guo, - Bioactive Diterpenoids from the Leaves of Callicarpa macrophylla, J Nat Prod. 78(7) (2015) 1563-1569.
Sony Jayaraman, E. Jayadevi variyar, - Evaluation of immunomodulatory and antioxidant activities of polysaccharides isolated from callicarpa macrophylla Vahl, Int J Pharm Pharm Sci, 7 (9) (2015) 357-360.
Ramesh Patel1 and Talha Jawaid, - Hepatoprotective activity of aerial parts of plant extract of Callicarpa macrophylla in rats, Pharmacy and Pharmacology Research, 2(1) (2014) 1-8.
G. Appalaraju, Ch. Siva Reddy, Ch. Venkateswara Reddy, G. Rajani, Ch. Nithin, Akondi Butchi Raju, - Anti diabetic activity of polyherbal extract on Streptozotocin induced diabetes in Wistar rats, Annals of Biological Research, 5 (6) (2014) 39-46.
Barkatullah, Muhammad Ibrar, Muhammad Nafees, Abdur Rauf, Haroon Khan, - Cytotoxic, acute toxicity and phytotoxic activity of Callicarpa macrophylla in various models, American Journal of Biomedical and Life Sciences, 3(2-1) (2015) 1-4.
John GoadL., Akihisa T. - Analysis of sterols, Chapman & Hall, London, (1997) 324-333.
Luhata Lokadi Pierre, Munkombwe Namboole Moses, - Isolation and Characterisation of Stigmasterol and Β - Sitosterol from Odontonema Strictum (Acanthaceae), Journal of Innovations in Pharmaceuticals and Biological Sciences, 2 (1), 88-95, 2015.
Vitus A. Nyigo, Xolani Peter, Faith Mabiki, Hamisi M. Malebo, Robinson H. Mdegela, Gerda Fouche, -Isolation and identification of euphol and β-sitosterol from the dichloromethane extracts of Synadenium glaucescens, The Journal of Phytopharmacology 5(3) (2016) 100-104.
Tania Peshin1 and H. K. Kar2 , - Isolation and Characterization of β-Sitosterol-3-O-β-D-glucoside from the Extract of the Flowers of Viola odorata, British Journal of Pharmaceutical Research 16 (4) (2017) 1-8.
Yuan-Chuen Wang, Wan-Yu Li, Deng-Chyang Wu, Jeh-Jeng Wang, Cheng-Hsun Wu, Jyun-Ji Liao, and Cheng-Kun Lin, - In Vitro Activity of 2-methoxy-1,4-naphthoquinone and Stigmasta-7,22-diene-3β-ol fromImpatiens balsamina L. against Multiple Antibiotic-Resistant Helicobacter pylori. Evid Based Complement Alternat Med, 4 (2011) 704-721.
Shashi B. Mahato and Asish P. Kundu. -13C-NMR spectra of pentacyclic triterpenoids – A compilation and some salient features. Phytochemistry, 37 (5) (1994) 1517-1575.
Nkeoma Nkasi Okoye, Daniel Lotanna Ajaghaku, Henry Nnaemeka Okeke, Emmanuel Emeka Ilodigwe, Chukwuemeka Sylvester Nworu, and Festus Basden C. Okoye, - beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity, Pharm Biol, 52 (11) 2014 1478–1486.
Nomoto K., Ruedi P., Eugster C. H., Helv. - Rastronole A, B, C, D, E, F, G und H; eine Gruppe multioxygenierter Diterpenbitterstoffe der ent‐Kauran‐Reihe aus Englerastrum scandens A, Chim. Acta, 59 (3) (1976) 772—802.
Pham Thi Hong Minh, Pham Hoang Ngoc, Dang Ngoc Quang, Toshihiro Hashimoto, Shigeru Takaoka, and Yoshinori Asakawa, - A Novel ent-Kaurane Diterpenoid from the Croton tonkinensis gagnep, Chem. Pharm. Bull. 51(5) 590—591 (2003)
Fumihiro Nagashima, Masuo Kondoh, Toshinari Uematsu, Akiko Nishiyama, Sayaka Saito, Masao Sato, and Yoshinori Asakawa, - Cytotoxic and Apoptosis-Inducing ent-Kaurane-Type Diterpenoids from the Japanese Liverwort Jungermannia truncata N, Chem. Pharm. Bull. 50 (6) (2002) 808—813.
Vinay Kumar Verma, N.U. Siddiqui and Mohd. Aslam, - A new kauran diterpen from the leaves of Calicarpa macrophylla Vahl, International Research Journal of Pharmacy 3 (5) (2012) 178-179.
M.Jaensch, J. Jakupovic, H. sanchez and X.A. Dominguez, - Diterpenes from hoffmannia strigillosa, Phytochemistry, 29 (11) (1990) 3587-3590.
Jing Xu, Yihang Sun, Meicheng Wang, Quanhui Ren, Shen Li, Hao Wang, Xiaocong sun, Da-Qing Jin, Hongwei Sun, Yasushi Ohizumi, and Yuanqiang Guo, - Bioactive diterpenoids from the leaves of Callicarpa macrophylla, Journal of Natural Products, 78(7) (2015) 1563-1569.
How to Cite
Authors who publish with Vietnam Journal of Science and Technology agree with the following terms:
- The manuscript is not under consideration for publication elsewhere. When a manuscript is accepted for publication, the author agrees to automatic transfer of the copyright to the editorial office.
- The manuscript should not be published elsewhere in any language without the consent of the copyright holders. Authors have the right to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of their work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are encouraged to post their work online (e.g., in institutional repositories or on their websites) prior to or during the submission process, as it can lead to productive exchanges or/and greater number of citation to the to-be-published work (See The Effect of Open Access).