ALGINATE/CHITOSAN FILM LOADING GOLDEN FLOWER TEA (CAMELLIA CHRYSANTHA) EXTRACT: PREPARATION AND CHARACTERIZATION
Keywords:Golden Flower Tea extract, Camellia chrysantha, alginate, chitosan, composite film
Golden Flower Tea has the scientific name Camellia chrysantha. It can effectively enhance human immune function, prevent and fight cancer, be anti-aging and prolongs life, and be a powerful antioxidant. Polymer systems loading Golden Flower Tea extract can enhance their solubility and effectivity in simulated body solutions such as stomach or intestine environments. In this paper, chitosan and alginate, two natural polymers, were selected for the preparation of chitosan/alginate loading Golden Flower Tea extract thanks to their many advantages. The method was used in preparation of chitosan/alginate film loading Golden Flower Tea extract is solution method with appreciated solutions for each substance. The suitable ratio of alginate/chitosan obtained from previous studies is 7/3. The characteristics of these films are evaluated by Fourier Transform Infrared (FT-IR) spectroscopy, Scanning Electron Microscopy (SEM), and Differential Scanning Calorimetric (DSC) methods. The obtained results show that polyphenols interact and disperse regularly in polymer matrix.
Gavhane Yogeshkumar N., Gurav Atul S and Yadav Adhikrao V. - Chitosan and its applications: A review of literature. International Journal of Research in Pharmaceutical and Biomedical Sciences 4(1) (2013) 312-331.
Loreana L., Alexandre L.P., Valfredo F., Mauro C.M.L, Hellen K.S. - Development and evaluation of pH-sensitive sodium alginate/chitosan microparticles containing the antituberculosis drug rifampicin. Materials Science and Engineering C 39 (2014) 161–167.
Manju B., Pawan K., Meenu C., Rajesh T. - Synthesis, characterization of nisin loaded alginate-chitosan-pluronic composite nanoparticles and evaluation against microbes. LWT - Food Science and Technology 59 (2014) 1093-1099.
Cui-Yun Y., Xi-Chen Z., Fang-Zhou Z., Xian-Zheng Z., Si-Xue C., Ren-Xi Z. - Sustained release of antineoplastic drugs from chitosan-reinforced alginate microparticle drug delivery systems. International Journal of Pharmaceutics 357 (2008) 15-21.
Miloslava R., Kateﬁina D., Lenka K. - Stability testing of alginate-chitosan films for colon drug delivery. Ceska a Slovenska Farmacie 61 (2012) 26–33.
Mohy Eldin M.S., Omer A.M., Wassel M.A., Tamer T.M., Abd Elmonem M.S., Ibrahim S.A. - Oval smart pH sensitive chitosan grafted alginate hydrogel microcapsules for oral protein delivery: I. preparation and characterization. International Journal of Pharmacy and Pharmaceutical Sciences 7(10) (2015) 331-337.
Shinichi W., Katsuya S., Takumi Y., Noriaki H., Masahiro S., Hiroaki A. - Effect of oral mucosal adhesive films containing ginsenoside Rb1 on 5-fluorouracil-induced oral mucositis in hamsters. European Journal of Pharmacology 616 (2009) 281–286.
Vipin B., Pramod K.S., Nitin S., Om P.P. and Rishabha M. - Applications of chitosan and chitosan derivatives in drug delivery. Advances in Biological Research 5 (1) (2011) 28-37.
Mohy Eldin M.S., Omer A.M., Wassel M.A., Tamer T.M., Abd Elmonem M.S., Ibrahim S.A. - Oval smart pH sensitive chitosan grafted alginate hydrogel microcapsules for oral protein delivery: I. preparation and characterization. International Journal of Pharmacy and Pharmaceutical Sciences 7 (10) (2015) 331-337.
Chinh N.T., Ly N.T.H, Mai T.T., Trang N.T.T., Loc T.T., Giang L.D., Tung N.Q, Hoang T. - Characteristic and properties of chitosan/alginate polymer blend carrying lovastatin drug. Journal of Science and Technology 54 (2B) (2016) 118-124.
Lai W., Debmalya R., Sen S. L., Sheng T. Y. and Li S. - Hypoglycemic effect of Camellia chrysantha extract on type 2 diabetic mice model. Bangladesh J Pharmacol 12 (2017) 359-363.
Jin-Bin W., Xiong L., Hui S., Yong-Hong L., Yu-Zheng P., Jun-Xiang R., Xia Q., Yong-Xin C., Cai-Li N., Zhi-Heng S. - Characterization and determination of antioxidant components in the leaves of Camellia chrysantha (Hu) Tuyama based on composition activity relationship approach. Journal of Food and Drug Analysis 23 (2015) 40-48
Yokozawa K. - Antioxidative activity of green polyphenol in cholesterol-fed rats, National Institutes of Health 50(12) (2002) 3549-3552.
Shirode A. B., Bharali D. J., Nallanthighal S., Coon J. K., Mousa S. A., Reliene R. - Nanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention. Int J Nanomed 10 (2015) 475–484.
Authors who publish with Vietnam Journal of Science and Technology agree with the following terms:
- The manuscript is not under consideration for publication elsewhere. When a manuscript is accepted for publication, the author agrees to automatic transfer of the copyright to the editorial office.
- The manuscript should not be published elsewhere in any language without the consent of the copyright holders. Authors have the right to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of their work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are encouraged to post their work online (e.g., in institutional repositories or on their websites) prior to or during the submission process, as it can lead to productive exchanges or/and greater number of citation to the to-be-published work (See The Effect of Open Access).