SEPARATION AND HPLC QUANTITATIVE ANALYSIS OF MURRAYAFOLINE A FROM THE ROOTS OF GLYCOSMIS STENOCARPA

Authors

  • Tran Quoc Toan Institute of Natural Products Chemistry, VAST, 18 Hoang Quoc Viet road, Cau Giay, Hanoi

DOI:

https://doi.org/10.15625/2525-2518/54/2C/11884

Keywords:

Glycosmis stenocarpa, Rutaceae, carbazole alkaloid, Murrayafoline A.

Abstract

In this study, we investigated two methods for the separation and purification of alkaloid
Murrayafoline A from the roots of the Vietnamese plant Glycosmis stenocarpa and developed an
HPLC method for the determination of its contents in plant materials and the methanol extract.
The yield of Murrayafoline A using steam distillation method was 1.5 times higher than the
separation method using column chromatography. By HPLC method, the content of
Murrayafoline A was determined to be 0.38 % (w/w) in the roots and 16.69 % (w/w) in the
methanol extract of G. stenocarpa.

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Published

2018-03-19

Issue

Section

Articles