Anthraquinones from the roots of Paederia scandens

Đặng Ngọc Quang

Abstract


Chemical investigation on the ethyl acetate extract of the roots of Vietnamese Paederia scandens resulted in the isolation of one new anthraquinone, 1,3-Dihydroxy-2,4-dimethoxy-9,10-anthraquinone (1), together with three known anthraquinones, 2-Hydroxy-1,4-dimethoxy-9,10-anthraquinone (2), 1-Methoxy-2-methoxymethyl-3-hydroxy-9,10-anthraquinone (3), 1-Hydroxy-2-hydroxymethyl-9,10-anthraquinone (4). Their structures were elucidated by the combination of 2D NMR, IR, UV and high resolution EI-MS spectroscopy. These anthraquinones (1 - 4) showed strong antimicrobial activity.


Keywords


Anthraquinone, Paederia scandens, Rubiaceae, Antimicrobial.