Open Access Open Access  Restricted Access Subscription Access

Two cycloartanes-type triterpenoid from Homonoia riparia Lour

Le Thi Huyen, Nguyen Thi Son, Phan Van Kiem


Using various chromatography methods, two known cycloartanes, 24-methylenecycloartane-3β,6β,7β,16β-tetraol (1) and riparsaponin (2), together with two known flavonol glycosides, quercetin 3-O-β-D-glucopyranoside (3) and quercetin 3-O-α-L-rhamnopyranosyl (1→6) β-D-glucopyranoside (4) were isolated from the methanol extract of the leaves of Homonoia riparia Lour. Their structures were determined by MS and 1D-, 2D-NMR spectra, as well as by comparison with those reported in the literature.

Keywords. Homonoia riparia, cycloartane, flavonol glycoside.


Homonoia riparia, cycloartane, flavonol glycoside


V. V. Chi. The Dictionary of Medicinal Plants in Vietnam, Medical Publising House, 574-575 (2012).

U. C. Bapat, D. R. Mhapsekar. Phytochemical investigations and antimicrobial and anticancer activities of Homonoia riparia Lour, Journal of Pharmacy and Pharmaceutical Sciences, 237-243 (2014).

J. -H. Yu, Y. Shen, H.-B. Liu, Y. Leng, H. Zhang, J.-M. Yue. Dammarane-type triterpenoids as 11β-HSD1 inhibitors from Homonoia riparia, Organic & Biomolecular Chemistry, 12, 4716-4722 (2014).

S. -M. Yang, X. -K. Liu, C. Qing, D. -G. Wu, D. -Y. Zhu. Chemical constituents from the roots of Homonoia riparia, Yao Xue Xue Bao, 42, 292-296 (2007).

I. Lee, J. Kim, Y. S. Kim, N. H. Yoo, C.-S. Kim, K. Jo, J.-H. Kim, T. T. Bach, J. S. Kim. Cycloartane-type triterpenes from the leaves of Homonoia riparia with VEGF-induced angiogenesis inhibitory activity, Journal of Natural Products, 75, 1312-1318 (2012).

F. Xu, X. Zhao, L. Yang, X. Wang, J. Zhao. A new cycloartane-type triterpenoid saponin xanthine oxidase inhibitor from Homonoia riparia Lour, Molecules, 19, 13422-13431 (2014).

H. -Y. Lin, Y. -H. Kuo, Y. -L. Lin, W. Chiang. Antioxidative effect and active components from leaves of Lotus (Nelumbo nucifera), Journal of Agricultural and Food Chemistry, 57, 6623-6629 (2009).

M. -A. Beck, H. Häberlein. Flavonol glycosides from Eschscholtzia californica, Phytochemistry, 50, 329-332 (1999).

Full Text: PDF


  • There are currently no refbacks.