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Large-scale fabrication of colloidal nano-sized CuCl solution with high concentration for using as fungicide for plant

Bui Duy Du, Lai Thi Kim Dung, Le Nghiem Anh Tuan, Nguyen Quoc Hien


Synthesis of nano-sized CuCl with Cu concentration from 4,000 to 6,000 ppm dispersed in chitosan solution (nano-sized CuCl/CTS) using CuSO4.5H2O as the precursor and NaHSO3 as the reducing agent in HCl acid medium on large scale of 1.000 kg/batch was carried out. The obtained nano-sized CuCl/CTS samples were characterized by transmission electron microscopy (TEM) and X-ray powder diffraction (XRD). Based on the obtained results, the reaction factors for fabrication of the colloidal nano-sized CuCl/CTS solution with Cu concentration of 5,000 ppm and CuCl nanoparticle size of about 7.7 nm dispersed in 1 % chitosan solution were selected for application in agriculture as a fungicide for plant protection.

Keywords. Nano-sized CuCl, NaHSO3, HCl, chitosan.


Nano-sized CuCl, NaHSO3, HCl, chitosan


D. Rusjan. Copper in horticulture, in “Fungicides for Plant and Animal Diseases” (Eds. By Dhanasekaran, N. Thajuddin and A. Panneerselvam), published by Intech, Rijeka, Croatia, 257-278 (2012).

P. K. Khanna, S. Gaikwad, P. V. Adhyapak, N. Singh, R. Marimuthu. Synthesis and characterization of copper nanoparticles, Materials Letters, 61, 4711-4714 (2007).

Y. Huang, F. Shen, J. La, Ge. Luo, J. Lai, C. Liu, G. Chu. Synthesis and Characterization of CuCl Nanoparticles in Deep Eutectic Solvents, Particulate Science and Technology, 31, 81-84 (2013).

N. N. Hanh, V. H. Thao. Green synthesis of copper oxide nanoparticles, Journal of Science & Technology Development, 14(K3), 61-69 (2011).

N. M. Zain, A. G. F. Stapley, G. Shama. Green synthesis of silver and copper nanoparticles using ascorbic acid and chitosan for antimicrobial applications, Carbohydrate Polymers, 112, 195-202 (2014).

S. Shankar, J. W. Rhim. Effect of copper salts and reducing agents on characteristics and antimicrobial activity of copper nanoparticles, Materials Letters, 132, 307-311 (2014).

C. V. Du, N. T. P. Phong, N. X. Chuong. Synthesis and characterization of copper nanoparticles contract in glycerin using hydrazine hydrate reduction methods combined with microwave heating, Vietnam Journal of Science and Technology, 52(1C), 75-84 (2014).

C. V. Du, N. T. P. Phong, N. T. K. Phuong. Synthesis and adjustment of copper nanoparticle size contract in glycerin/PVP system, Vietnam Journal of Chemistry, 51(2C), 745-749 (2013).

H. T. Zhu, C. Y. Zhang, Y. S. Yin. Rapid synthesis of copper nanoparticles by sodium hypophosphite reduction in ethylene glycol under microwave irradiation, Journal of Crystal Growth, 270, 722-728


M. Yang, J. Xia. Preparation and characterization of CuCl nanorods using CuO as the precursor, Applied Mechanics and Materials, 347-350, 1196-1198 (2013).

G. Suyal, M. Mennig, H. Schmidt. Sol–gel synthesis of cuprous halide nanoparticles in a glassy matrix and their characterization, Journal of Materials Chemistry, 13, 1783-1788 (2003).

S. Hamad, G. K. Podagatlapalli, S. P Tewari, S. V. Rao. Synthesis of Cu2O, CuCl, and Cu2OCl2 nanoparticles by ultrafast laser ablation of copper in liquid media, PRAMANA-Journal of Physics, 82(2), 331-337 (2014).

S. Bautista-Banos, A. N. Hernández-Lauzardo, M. G. Velázquez-del Valle, M. Hernández-López, E. Ait Barka, E. Bosquez-Molina, C.L. Wilson. Chitosan as a potential natural compound to control pre and postharvest diseases of horticultural commodities, Crop Protection, 25, 108-118 (2006).

W. Xia, P. Liu, J. Zhang, J. Chen. Biological activities of chitosan and chitooligo-saccharides, Food Hydocolloids, 25, 170-179 (2011).

E. Ramanathan. Heavy metals, in “IAEEE Chemistry”, published by Sura College of Competition, 240-255 (2006).

B. D. Du, D. V. Phu, N. N. Duy et al. Preparation of colloidal silver nanoparticles in poly(N-vinyl pyrrolidone) by gamma irradiation, J. Exp. Nanosci., 3(3), 207-213 (2008)

B. D. Du et al. Synthesis and investigation of activities against fungal pathogens and nematodes on plant roots of CuCl nanoparticles, Res. Project. Inst. Appl. Mater. Sci. (2015).

G. A. Martinez-Catanon, N. Nino-Martinez, F. Martinez-Gutierrez, J. R. Martinez-Mendoza, F. Ruiz. Synthesis and antimicrobial activity of silver with different sizes, J. Nanopart. Res., 10, 1343-1348 (2008).

M. Rhazi, J. Desbrieres, A. Tolaimate, M. Rinaudo, P. Vottero, A. Alagui. Contribution to the study of the complexation of copper by chitosan and oligomers, Polymers, 43 1267-1276 (2002).

N. N. Duy, D. V. Phu, N. T. Anh, N. Q. Hien. Synergistic degradation to prepare oligochitosan by -irradiation of chitosan solution in the presence of hydrogen peroxide, Radiation Physics and Chemistry, 80, 848-853 (2011).

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