Open Access Open Access  Restricted Access Subscription Access

Một số hợp chất flavonoid từ quả cây Ba soi khe núi

Lê Trần Nguyên Vũ, Đỗ Thị Quỳnh, Trần Đăng Thạch, Đoàn Thị Mai Hương, Phạm Văn Cường

Abstract


The genus Macaranga belongs to the family Euphorbiaceae comprises of about 300 species that are native mainly to the tropics of Africa, Asia, Australia and the Pacific regions. Thirteen different species of this genus occur in Vietnam, and Macaranga sampsonii has been used in traditional medicine to treat swellings, cuts, sores. From the fruit of this plant, four flavonoids macarecurvatin A (1), 8-dimethylallylisosakuranetin (2), 8-prenylnaringenin (3),  6,8-diprenylaromadendrin (4) were isolated. Their structures were elucidated by IR, MS and NMR spectroscopic methods.

Keywords. Macaranga sampsonii, Euphorbiaceae, flavonoids, macarecurvatin A.


Keywords


Macaranga sampsonii, Euphorbiaceae, flavonoids, macarecurvatin A

References


Lê Khả Kế. Cây cỏ thường thấy ở Việt Nam, tập 2, Nxb. Khoa học và Kĩ thuật Thành phố Hồ Chí Minh (1971).

Phạm Hoàng Hộ. Cây cỏ Việt Nam, Nxb. Trẻ, tập 2, 259 (1998).

X. Li, L. Xu, P. Wu, H. Xie, Z. Huang, W. Ye, X. Wei. Prenylflavonols from the leaves of Macaranga sampsonii, Chem. Pharm. Bull., 57(5), 495-498 (2009).

R. M. Ngoumfo, G. E. Ngounou, C. V. Tchamadeu, M. I. Qadir, C. D. Mbazoa, A. Begum, F. N. Ngninzeko, D. Lontsi, and M. I. Choudhary. Inhibitory Effect of Macabarterin, a Polyoxygenated Ellagitannin from Macaranga barteri, on Human Neutrophil Respiratory Burst Activity, Journal of Natural Products, 71, 1906-1910 (2008).

T. Mulyadi, S. T. Tjitjik. Dihydroflavanols from the leaves of Macaranga recurvate and their cytotoxic and antioxidant activities, Journal of Chemical and Pharmaceutical Research, 6(7), 90-95 (2014).

J. M. Joseph. Phytochemistry and pharmacology of the genus Macaranga: A review, J. Med. Plants Res., 78, 489-503 (2014).

M. R. Loizzo, A. Said, R. Tundis, U. W.Hawas, K. Rashed, F. Menichini, N. G. Frega, F. Menichini. Antioxidant and Antiproliferative Activity of Diospyros lotus L. Extract and Isolated compound, Plant Foods Hum Nutr, 64, 246-270 (2009).

B. Agnieszka, T. Tomasz, and H. Ewa. Biotransformation of the Phytoestrogen 8-Prenylnaringenin, Z. Naturforsch, 65c, 603-606 (2010).

K. M. Meragelman, T. C. McKee, and M. R. Boyd. Anti-HIV Prenylated Flavonoids from Monotes africanus, Journal of Natural Products, 64, 546-548 (2001).


Full Text: PDF

Refbacks

  • There are currently no refbacks.