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Thành phần hóa học cây Cóc đỏ (Lumnitzera littorea) thu hái tại tỉnh Thừa Thiên Huế, Việt Nam

Phạm Thị Huyền, Đào Đức Thiện, Trần Văn Lộc, Trần Văn Sung, Trần Thị Phương Thảo


From the ethyl acetate and methanol extracts of the leaves and stems of Lumnitzera littorea (Jack) Voigt., collected in Thua Thien-Hue province, eleven compounds have been isolated. Their structures were elucidated as two resorcinolic lipids (1,3-dihydroxy-2-methyl-5-tridecylbenzene 1, 1,3-dihydroxy-5-nonadecylbenzene 2), two flavonoids (quercetin 3 and astragalin 4), two hexitols (1-acetyl-D-mannitol 5 and D-mannitol 6), α-D-glucopyranosyl-β-D-glucopyranoside (Neotrehalose 7) as octaacetate, fructopyranose as tetraacetate (8), β-sitosterol glycoside (9), β-sitosterol (10) and stigmasterol (11) as a mixture of 1:1 ratio. All of these compounds have been isolated for the first time from Lumnitzera littorea.

Keywords. Lumnitzera littorea, sterols, resorcinolic lipids, flavonoids, hexitols.


Lumnitzera littorea, sterols, resorcinolic lipids, flavonoids, hexitols.


Võ Văn Chi. Từ điển thực vật thông dụng, Nxb. Khoa học và Kỹ thuật, Hà Nội, 2, 1614-1615 (2004).

Sách đỏ Việt Nam, Nxb. Khoa học tự nhiên và Công nghệ, Hà Nội, phần II. Thực vật, 160-161 (2007).

Quách Văn Toàn Em. Nghiên cứu ảnh hưởng của loài cây Cóc đỏ (Lumnitzera littorea (Jack) Voigt.) với các chế độ muối khác nhau ở giai đoạn vườn ươm, Báo cáo tổng kết đề tài NCKH cấp trường, Khoa Sinh học, ĐHSP HCM (2008).

Wu J., Xiao Q., Xu J., Li M. Y., Pan J. Y., Yang M. H. Natural products from true mangrove flora: source, chemistry and bioactivities, Nat. Prod. Rep., 25, 955-981 (2008).

Kazantzoglou G., Magiatis P., Kalpoutzakis E., Skaltsounis A. L. Polygonophenone, the first Mem-Substituted natural product, from Polygonum maritimum, Journal of Natural Products, 72(2), 187-189 (2009).

Arisawa M., Ohmura K., Kobayashi A., Morita N. A cytotoxic constituent of Lysimachia japonica Thunb.(Primulaceae) and the structure – activity relationships of related compounds, Chem. Pharm. Bull., 37(9), 2431-2434 (1989).

Amico V., Biondi D. Three acetogenins from the brown alga Caulocystis Cephalornithos, Journal of Natural Products, 53(5), 1379-1382 (1990).

Jong Y. S., Eun A. M., Myun B. H. et al. Steroids from the aerial parts of Artemisia princeps Pampanini, Korean J. Medicinal Crop Sci., 14(5), 273-277 (2006).

Moufok Soumia, Haba Hamada, Lavaud Catherin, Long Christophe, Benkhaled Mohamed. Chemical constituents of Centaurea omphalotricha Coss. & Durieu ex Batt. & Trab., Rec. Nat. Prod., 6(3), 292-295 (2012).

L. Omur Demirezer et al. Iridoids, flavonoids and monoterpene glycosides from Galium verum subsp. Verum, Turk. J. Chem., 30, 525-534 (2006).

Angyal S. J. et al. Conformations of acyclic sugar derivatives (Part II): Determination of the conformations of alditol acetates in solution by the use of 250-MHz N.M.R. spectra, Carbonhyd. Res., 23, 121-134 (1972).

Angyal S. J. et al. The 13 C NMR. Spectra of alditol, Carbohydrate Research, 84, 201-209 (1980).

Tor E.C.L. R., Morten Meldel & Klaus Bock. Synthesis of Unsymmetrical Trehalose Analogues by Silver Trifluoromethanesulphonate Promoted Glycosylations, Journal of Carbohydrate Chemistry, 14(2), 197-211 (2006).

Lichtcnthaler F. W., Klotz J., Flath F. J. Acylation and Carbamoylation of D-Fructose: Acyclic, Furanoid and Pyranoid Derivatives and Their Conformational Features, Leibigs Ann., 2069-2080 (1995).

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