NGHIÊN CỨU HIỆU ỨNG ĐỒNG VẬN CẮT MẠCH CHITOSAN BẰNG BỨC XẠ GAMMA Co-60 KẾT HỢP VỚI HYDROPEROXIT

Abstract

Chitosan from squid pens with deacetylation degree of about 70% and molecular weight (M_w0) 91.5 ´ 10³ in dilute lactic acid solution containing H₂O₂ (1%) was effectively degraded by irradiation with gamma Co-60 radiation (1.33 kGy/h) in dose range up to 16 kGy. Based on the results of M_w measured by gel permeation chromatography (GPC), the synergic effect for degradation of chitosan  was calculated to be of 58.4% at 4 kGy and gradually decreased to 0.2% at 16 kGy. The values of radiation scission yield (G_s) were found out to be 2.2 and 0.2 mmol/J for chitosan in solution of 5% with and without H₂O₂ (1%), respectively. Deacetylation degrees of degraded chitosan measured from infrared (IR) spectra were almost unchanged.