STRUCTURE ELUCIDATION AND CYTOTOXIC ACTIVITY OF ATTENUATOSIDE B-1, PLANCISIDE A, AND CULCITOSIDE C2 FROM THE STARFISH ACANTHASTER PLANCI

Le Thi Vien, Tran Thi Hong Hanh, Phan Thi Thanh Huong, Do Thi Thao, Nguyen Van Thanh, Nguyen Xuan Cuong, Nguyen Hoai Nam

Abstract


Detailed analysis of the 1D and 2D NMR data and comparison with the reported values, the structures of attenuatoside B-1 (1), planciside A (2), and culcitoside C2 (3) from starfish Acanthaster planci were clearly elucidated. Culcitoside C2 (3) showed weak cytotoxic activity against five human cancer cell lines including HepG2, KB, LNCaP, MCF7, and SK-Mel2.

Keywords


Acanthaster planci; starfish; steroid glycoside; cytotoxic activity

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Published by Vietnam Academy of Science and Technology