Tran Thu Huong, Ha Manh Tuan, Le Huyen Tram, Nguyen Van Thong, Nguyen Hoang Minh, Tran Thi Minh, Dinh Thi Thu Hien, Tran Thuong Quang, Le Thi Thuy, Nguyen Tuan Anh


Abstract. Hibiscus sabdariffa L. is an annual, herbaceous medicinal plant that belongs to the Malvaceae family. This plant is believed to be native to Western Africa, cultivated and harvested widely in tropical and subtropical countries. The calyx is commercially important in the food industry for the production of beverages and foods such as tea, juices, jams, jellies, and syrup. Besides, various parts of the sorrel plant have been used in folk medicine for the prevention of diseases such as cardiovascular disease and hypertension. However, to date, the studies on the chemical composition as well as the biological activity of H. sabdariffa are still limited. In this study, four flavonoids, including tiliroside, quercetin-3-O-(6''-O-(E)-p-coumaryl-β-D-glucopyranoside, isoquercetin, and quercetin were isolated from the calyx of H. sabdariffa collected in Bac Giang province, Viet Nam. In addition, the methanol extract of the H. sabdariffa calyx showed the ability to scavenge DPPH free radicals with SC50 values ranging from 103.61-119.16 µg/ml, in comparison with that of the positive control, ascorbic acid (SC50 = 10.75 µg/ml).


Hibiscus sabdariffa, Hibiscus, flavonoids, antioxidants, DPPH

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