SOME TERPENE COMPOUNDS ISOLATED FROM CALLICARPA MACROPHYLLA (L.) SPECIES IN VIETNAM

Lam Tien DO, Lam Tien DO, Quan Minh PHAM, Thu Le Thi VU, Thu Le Thi VU, Hong Van Thi NGUYEN, Hong Van Thi NGUYEN, Inh Thi CAM, Inh Thi CAM, Thu Thuy Thi TA, Thu Thuy Thi TA, Long Quoc PHAM, Long Quoc PHAM, Hong Minh Thi PHAM, Hong Minh Thi PHAM

Abstract


Callicarpa macrophylla L. (Tu Chau la to) usually used in Vietnam traditional medicine for gastrointestinal bleeding, nosebleeds, in addition, it is also used for treating osteoarthritis pain. Phytochemical investigation of the n-hexan and ethyl acetate extract of Callicarpa macrophylla L. led to the isolation of β-sitosterol (1), β-sitosterol-3-O-β-D-glucopyranoside (2), stigmasta-7,22-dien-3β-ol (3), β-amyrin (4), ent-1α-acetoxy-7β,14α-dihydroxy-kaur-16-en-15-on (5) và ent-7β,16,17,18-tetrahydroxy-kaur-16-en-15-on (6). Their chemical structures were determined by spectroscopic methods including MS, 1D, 2D NMR and comparing with those reported in previous papers. Three compounds 4, 5, 6 were isolated for the first time from Callicarpa macrophylla  plant.


Keywords


Callicarpa macrophylla, sterol, triterpene and diterpene

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DOI: https://doi.org/10.15625/2525-2518/56/4A/13061

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