SIMULTANEOUS DETERMINATION OF DOPAMINE IN THE PRESENCE OF ASCORBIC ACID AND URIC ACID BY ELECTROCHEMICALLY OXIDIZED SCREEN PRINTED CARBON ELECTRODE

Nguyen Xuan Viet

Abstract


This research reported the simple method to determine of dopamine (DA) in the simultaneous presence of ascorbic acid (AA) and uric acid (UA). Three – electrode system manufactured by screen printing method was used due to its disposal and low cost. The screen printed carbon electrode (SPCE) was oxidized by electrochemical technique in acid medium. The capacity of oxidized electrode for selective detection of dopamine was confirmed in a sufficient amount of ascorbic acid and uric acid. The large separated peaks of DA from ascorbic acid and uric acid are observed. The peak separation between UA and DA, DA and AA was 110 mV and 160 mV, respectively. The bare SPCE cannot determine simultaneously AA and DA due to the overlap peaks of AA and DA around 0.2 V vs AgCl/Ag. This sensor also exhibited good sensitivity to DA with limit of detection 100 nM in phosphate buffer solution.


Keywords


dopamine, electrochemical sensor, electrochemical oxidization, SPCE.

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DOI: https://doi.org/10.15625/2525-2518/55/5B/12212 Display counter: Abstract : 80 views. PDF : 49 views.

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Published by Vietnam Academy of Science and Technology